Griffith Research Online
Griffith Research Online (GRO) is a digital archive of research and scholarship from Griffith University, Brisbane, Australia.
GRO delivers free online full-text versions of journal articles, conference papers, and more, where this is possible with the appropriate permissions of copyright owners. GRO increases the impact and influence of Griffith research and scholarship by ensuring it is visible, discoverable and accessible via search engines like Google and discovery services like the National Library’s Trove.
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Non-surgical osteoarthritis therapy, intra-articular drug delivery towards clinical applications
(Journal of Drug Targeting, 2020)Osteoarthritis (OA)is a common orthopaedic disease in middle-aged and aged people. To date, no disease-modifying drug is available to prevent the progression of OA. Surgical treatment of OA has complications such as pain ...JOURNAL ARTICLE -
Human β-defensin 3 gene modification promotes the osteogenic differentiation of human periodontal ligament cells and bone repair in periodontitis
(International Journal of Oral Science, 2020)Efforts to control inflammation and achieve better tissue repair in the treatment of periodontitis have been ongoing for years. Human β-defensin 3, a broad-spectrum antimicrobial peptide has been proven to have a variety ...JOURNAL ARTICLE -
The Development of Extracellular Vesicle-Integrated Biomaterials for Bone Regeneration
(Biomimicked Biomaterials: Advances in Tissue Engineering and Regenerative Medicine, 2020)The clinical need for effective bone regeneration remains in huge demands. Although autologous and allogeneic bone grafts are generally considered “gold standard” treatments for bone defects, these approaches may result ...BOOK CHAPTER -
Lithium silicate-based bioceramics promoting chondrocyte maturation by immunomodulating M2 macrophage polarization
(Biomaterials Science, 2020)Articular cartilage lesions occur frequently but unfortunately the damaged cartilage has a very limited intrinsic repair capacity. Since the cartilage damage can cause sterile inflammation, the effects of inflammation on ...JOURNAL ARTICLE -
3D printing of metal-organic framework nanosheets-structured scaffolds with tumor therapy and bone construction
(Biofabrication, 2020)After surgical resection for a bone tumor, the uncleared bone tumor cells can multiply and cause recurrence of the bone tumor. It is worthwhile to design a scaffold that kills the remaining bone tumor cells and repairs ...JOURNAL ARTICLE