Now showing items 20551-20570 of 54106

    • Genetic, historical and linguistic perspectives on the origin of the Kelantanese Malays 

      Loo, Keat Wei (Gene, 2014)
      The Kelantanese Malays who resided in the remote northeastern regions of the Malay Peninsula in the Kelantan state are believed to have a unique genetic signature. The objective of this review is to analyze the populational ...
    • Genetically and phenotypically distinct Pseudomonas aeruginosa cystic fibrosis isolates share a core proteomic signature 

      Penesyan, Anahit; Kumar, Sheemal S.; Kamath, Karthik Shantharam; Shathili, Abdulrahman M.; Venkatakrishnan, Vignesh; Krisp, Christoph; Packer, Nicolle H.; Molloy, Mark P.; Paulsen, Ian T. (PLoS One, 2015)
    • Genetically effective population sizes of Antarctic seals estimated from nuclear genes 

      Curtis, Caitlin; S. Stewart, Brent; A. Karl, Stephen (Conservation Genetics, 2011)
      We analyzed eight nuclear microsatellite loci in three species of Antarctic seals; Weddell seal (Leptonychotes weddellii; mean N = 163), crabeater seal (Lobodon carcinophaga; 138) and Ross seal (Ommatophoca rossii; 35). ...
    • Genetically modified Plasmodium highlights the potential of whole parasite vaccine strategies 

      F. Good, Michael (Trends in Immunology, 2005)
      A genetically modified malaria sporozoite might breathe new life into the traditional approach to vaccine development, that of using whole organisms. Mueller and colleagues recently knocked out a gene, UIS3, from the rodent ...
    • Genetics and cardiovascular disease: Design and development of a DNA biobank 

      Jayasinghe, Satyajit; Mishra, Akshay; Van Daal, Angela; Kwan, Edmond (Experimental and Clinical Cardiology, 2009)
      Coronary artery disease (CAD) is a complex disease with environmental and genetic determinants. Many other cardiovascular (CV) conditions also have a genetic basis. A positive family history of CV disease in first-degree ...
    • Genetics in field ecology and conservation 

      Fitzsimmons, Nancy; Sumner, Joanna (Reptile Ecology and Conservation: A Handbook of Techniques, 2016)
      This chapter discusses the importance of genetics in questions of ecology and conservation, as genetic analyses have provided tremendous insights into the behaviour of reptiles, their evolution, and the history and dynamics ...
    • The genetics of alphaviruses 

      Foo, Jolin; Chen, Javier; Herrero, Lara; Bettadapura, Jayaram; Narayan, Jayasuryan; Dar, Lalit; Broor, Shobha; Mahalingam, Suresh (Future Virology, 2011)
      Alphaviruses are emerging human pathogens that are transmitted by arthropod vectors. Their ability to infect a wide range of vertebrate hosts including humans, equines, birds and rodents has brought about a series of ...
    • The genetics of campylobacter lipopolysaccharide biosynthesis IN:Campylobacter 2nd Edition. Eds: I.Nachamkin & M.J.Blaser.381-403. 

      Korolik, Victoria; Fry, BN.; Oldfield, NJ.; Coloe, PJ.; Ketley, JM. (Campylobacter, 2000)
    • The genetics of endurance: Frequency of the ACTN3 R577X variant in Ironman World Championship athletes 

      Grealy, Rebecca; Smith, Carl; Chen, Timothy; Hiller, Doug; Haseler, Luke; Griffiths, Lyn (Journal of Science and Medicine in Sport, 2013)
      OBJECTIVES: To investigate the frequency of the ACTN3 R577X polymorphism in elite endurance triathletes, and whether ACTN3 R577X is significantly associated with performance time. DESIGN: Cross-sectional study. METHODS: ...
    • Genetics of Menstrual Migraine: The Molecular Evidence 

      Colson, Natalie; Fernandez, Francesca; Griffiths, Lyn (Current Pain and Headache Reports, 2010)
      Migraine is considered to be a multifactorial disorder in which genetic, environmental, and, in the case of menstrual and menstrually related migraine, hormonal events influence the phenotype. Certainly, the role of female ...
    • The Genetics of Migraine 

      Colson, Natalie; Lea, Rodney; Fernandez, Francesca; Griffiths, Lyn (Migraine Disorders Research Trends, 2008)
    • Genetics of Migraine: Implications for novel treatments 

      Griffiths, Lyn; Lea, Rodney; Colson, Natalie; Quinlan, Sharon; MacMillan, J. (3rd World Congress on Controversies in Neurology (CONy), 2009)
      Migraine is a severe neurological disorder that affects a significant proportion of the population. Prevalence estimates for the disorder vary between 12 and 25% depending on the population studied. The disorder has a ...
    • Genetics of thyroid lesions updated. (section Endocrine Pathology) 

      Lam, Alfred (Congress of the International Academy of Pathology 2014., 2014)
    • Genital herpes zoster as a consequence of cancer chemotherapy-induced immunosuppression: report of a case 

      Gopalan, Vinod; Nair, Raj; Pillai, Suja; Oberholzer, Theunis (Journal of Infection and Chemotherapy, 2012)
      Herpes zoster (HZ) is a clinical manifestation of the reactivation of the varicella zoster virus (VZV). HZ of the male genital area is a rarely reported condition. The exact mechanism of latency and reactivation of VZV in ...
    • Genome analysis of the anaerobic thermohalophilic bacterium Halothermothrix orenii 

      Mavromatis, Konstantinos; Ivanova, Natalia; Anderson, Iain; Lykidis, Athanasios; D. Hooper, Sean; Sun, Hui; Kunin, Victor; Lapidus, Alla; Hugenholtz, Philip; Patel, Bharat; C. Kyrpides, Nikos (PloS One, 2009)
      Halothermothirx orenii is a strictly anaerobic thermohalophilic bacterium isolated from sediment of a Tunisian salt lake. It belongs to the order Halanaerobiales in the phylum Firmicutes. The complete sequence revealed ...
    • The genome and developmental transcriptome of the strongylid nematode Haemonchus contortus 

      Schwarz, Erich; Korhonen, Pasi; Campbell, Bronwyn; Young, Neil; Jex, Aaron; Jabbar, Abdul; Hall, Ross; Mondal, Alinda; Howe, Adina; Pell, Jason; Hofmann, Andreas; Boag, Peter; Zhu, Xing-Quan; Gregory, T Ryan; Loukas, Alex; Williams, Brian; Antoshechkin, Igor; Brown, C Titus; Sternberg, Paul; Gasser, Robin (Genome Biology, 2013)
      Background The barber's pole worm, Haemonchus contortus, is one of the most economically important parasites of small ruminants worldwide. Although this parasite can be controlled using anthelmintic drugs, resistance against ...
    • Genome and transcriptome of the porcine whipworm Trichuris suis 

      Jex, Aaron; Nejsum, Peter; Schwarz, Erich; Hu, Li; Young, Neil; Hall, Ross; Korhonen, Pasi; Liao, Shengguang; Thamsborg, Stig; Xia, Jinquan; Xu, Pengwei; Wang, Shaowei; Scheerlinck, Jean-Pierre; Hofmann, Andreas; Sternberg, Paul; Wang, Jun; Gasser, Robin (Nature Genetics, 2014)
      Trichuris (whipworm) infects 1 billion people worldwide and causes a disease (trichuriasis) that results in major socioeconomic losses in both humans and pigs. Trichuriasis relates to an inflammation of the large intestine ...
    • A genome screen for multiple sclerosis in Italian families 

      Broadley, S; Sawcer, S; D'Alfonso, S; Hensiek, A; Coraddu, F; Gray, J; Roxburgh, R; Clayton, D; Buttinelli, C; Quattrone, A; Trojano, M; Massacesi, L; Compston, A (Genes and Immunity, 2001)
      We have screened the whole genome for linkage in 40 Italian multiplex families with multiple sclerosis using 322 markers. The GENEHUNTER-PLUS program was used to analyse these data and revealed eight regions of potential ...
    • A genome screen for multiple sclerosis in Sardinian multiplex families 

      Coraddu, F; Sawcer, S; D'Alfonso, S; Lai, M; Hensiek, A; Solla, E; Broadley, Simon; Mancosu, C; Pugliatti, M; MG, Morrosu; Compston, D Alastair S (European Journal of Human Genetics, 2001)
      The prevalence of multiple sclerosis in Sardinia is significantly higher than in neighbouring Mediterranean countries, suggesting that the isolated growth of the population has concentrated genetic factors which increase ...
    • Genome Sequence of Enterotoxigenic Escherichia coli Strain B2C 

      Thekke Palasseri, Vipin Madhavan; A. Steen, Jason; Hugenholtz, Philip; Sakellaris, Harry (Genome Announcements, 2014)
      Enterotoxigenic Escherichia coli (ETEC) is a major cause of diarrheal disease around the globe, causing an estimated 380,000 deaths annually. The disease is caused by a wide variety of strains. Here, we report the genome ...