Now showing items 32479-32498 of 54228

    • N(1),N(1)-Dimethyl-N(3)-(3-(trifluoromethyl)phenethyl)propane-1,3-diamine, a new lead for the treatment of human African trypanosomiasis 

      Pham, Ngoc; Deydier, Sophie; Labaied, Mehdi; Monnerat, Séverine; Stuart, Kenneth; Quinn, Ronald (European Journal of Medicinal Chemistry, 2014)
      The natural product, convolutamine I (1), has anti-trypanosomal activity however it has a high molecular weight of 473 due to a presence of 3 bromine atoms. The synthesis of the natural product convolutamine I (1) together ...
      JOURNAL ARTICLE
    • N- and O-glycomics from minor amounts of formalin-fixed, paraffin-embedded tissue samples 

      Hinneburg, Hannes; Schirmeister, Falko; Korac, Petra; Kolarich, Daniel (Methods in Molecular Biology, 2017)
      The availability of well-defined samples in sufficient numbers represents a major bottleneck for any biomarker related research. The utilization of preserved, archived and clinically well-described samples therefore holds ...
      JOURNAL ARTICLE
    • N-(2-Nitrobenzenesulfonyl)-L-alanine methyl ester 

      Bornaghi, Laurent; Poulsen, Sally-Ann; Healy, Peter; White, Alan (Acta crystallographica. Section E, Structure reports online, 2005)
      The structure of the title compound, C10H12N2O6S, has been determined as part of an ongoing investigation into the preparation of substituted amino acids suitable for the generation of combinatorial libraries. The molecular ...
      JOURNAL ARTICLE
    • N-(2-Nitrophenylsulfonyl)glycine methyl ester 

      Bornaghi, Laurent; Poulsen, Sally-Ann; Healy, Peter; White, Alan (Acta crystallographica. Section E, Structure reports online, 2005)
      The structure of the title compound, C9H10N2O6S, has been determined as part of an ongoing investigation into the preparation of N-allyl-substituted amino acids suitable for alkene cross-metathesis reactions in the generation ...
      JOURNAL ARTICLE
    • N-(4,6-Dimethylpyrimidin-2-yl)-4-(oxolan-2-ylamino)benzenesulfonamide 

      D. Arman, Hadi; Kaulgud, Trupta; R. T. Tiekink, Edward; Young, David (Acta Crystallographica. Section E: Structure Reports Online, 2009)
      The title compound, C16H20N4O 3S, adopts an l-shaped conformation, as seen by the dihedral angle of 76.93 (7)ࠦormed between the two aromatic rings. The most notable feature of the crystal packing is the formation of N- H?O ...
      JOURNAL ARTICLE
    • N-Acetylneuraminic acid derivatives and mimetics as anti-influenza agents 

      Thomson, Robin; von Itzstein, Mark (Carbohydrate-based Drug Discovery. Volume 2, 2003)
      BOOK CHAPTER
    • N-allyl-N-(2-nitrobenzenesulfonyl)-L-leucine methyl ester 

      Bornaghi, Laurent; Poulsen, Sally-Ann; Healy, Peter (ACTA Crystallographica Section E - Structure Reports Online, 2004)
      The structure of the title compound, C16H22N2O6S, has been determined as part of an ongoing investigation into the preparation of N-alkylated amino acid precursors for alkene cross-metathesis reactions for the generation ...
      JOURNAL ARTICLE
    • N-Allyl-N-(2-nitrobenzenesulfonyl)-L-phenylalanine methyl ester 

      Poulsen, Sally-Ann; Noack, Cassandra; Healy, Peter (ACTA Crystallographica Section E - Structure Reports Online, 2003)
      The structure of the title compound, C19H20N2O6S, has been determined as part of an ongoing investigation into the preparation of bis-N-alkyl�ed amino acids for subsequent alkene cross-metathesis reactions to generate ...
      JOURNAL ARTICLE
    • N-benzyl-2-(3-chloro-4-hydroxyphenyl)acetamide 

      Davis, Rohan; Healy, Peter (Acta crystallographica. Section E, Structure reports online, 2010)
      The title compound, C15H14ClNO2, was synthesized as part of a project to generate a combinatorial library based on the fungal natural product 2-(3-chloro-4-hydroxyphenyl)acetamide. It crystallizes as non-planar discrete ...
      JOURNAL ARTICLE
    • N-cinnamoyl-L-phenylalanine methyl ester 

      Bornaghi, Laurent; Poulsen, Sally-Ann; Healy, Peter; White, Alan (Acta Crystallographica. Section E: Structure reports online, 2008)
      JOURNAL ARTICLE
    • N-Cinnamoyl-L-valine methyl ester 

      Bornaghi, Laurent; Poulsen, Sally-Ann; Healy, Peter; White, Alan (Acta Crystallographica. Section E: Structure reports online, 2007)
      The crystal structure of the title compound, C15H19NO3, shows that the overall molecular conformation, which is approximately planar, is stabilized by intermolecular N-H...O hydrogen-bonding interactions.
      JOURNAL ARTICLE
    • N-glycan MALDI imaging mass spectrometry on formalin-fixed paraffin-embedded tissue enables the delineation of ovarian cancer tissues 

      Everest-Dass, Arun V.; Briggs, Matthew T.; Kaur, Gurjeet; Oehler, Martin K.; Hoffmann, Peter; Packer, Nicolle H. (Molecular and Cellular Proteomics, 2016)
      Ovarian cancer is a fatal gynaecological malignancy in adult women with a five-year overall survival rate of only 30%. Glycomic and glycoproteomic profiling studies have reported extensive protein glycosylation pattern ...
      JOURNAL ARTICLE
    • N-glycans modulate the function of human corticosteroid-binding globulin 

      Sumer-Bayraktar, Zeynep; Kolarich, Daniel; Campbell, Matthew P.; Ali, Sinan; Packer, Nicolle H.; Thaysen-Andersen, Morten (Molecular and Cellular Proteomics, 2011)
      Human corticosteroid-binding globulin (CBG), a heavily glycosylated protein containing six N-linked glycosylation sites, transports cortisol and other corticosteroids in blood circulation. Here, we investigate the biological ...
      JOURNAL ARTICLE
    • N-heterocyclic carbene Pt(II) complexes from caffeine: synthesis, structures and photoluminescent properties 

      Hu, Jian Jin; Bai, Shi-Qiang; Yeh, Hsiu Hsuan; J. Young, David; Chi, Yun; Andy Hor, T. (Dalton Transactions, 2011)
      JOURNAL ARTICLE
    • N-nitrosodimethylamine and trihalomethane formation and minimisation in Southeast Queensland drinking water 

      Knight, Nicole; Watson, Kalinda; Farré, Maria José; Shaw, Glendon (Environmental Monitoring and Assessment, 2012)
      This study assesses the prevalence of disinfection by-product (DBP) precursors in some Southeast Queensland drinking water sources by conducting formation potential experiments for the four regulated trihalomethanes (THMs), ...
      JOURNAL ARTICLE
    • N-of-1 randomized trials to assess the efficacy of gabapentin for chronic neuropathic pain 

      Yelland, Michael; J. Poulos, Christopher; I. Pillans, Peter; M. Bashford, Guy; Nikles, Catherine Jane; M. Sturtevant, Joanna; Vine, Norma; B. Del Mar, Christopher; J. Schluter, Philip; Tan, Meng; Chan, Jonathan; Mackenzie, Fraser; Brown, Robyn (Pain Medicine, 2009)
      Objective. The objective of this study was to compare the efficacy of gabapentin with placebo for neuropathic pain at the individual and population levels. Design. This study used an n-of-1 trial methodology with three ...
      JOURNAL ARTICLE
    • N-{2-[4-(Aminosulfonyl)phenyl]ethyl}-2-(4-hydroxy-phenyl)acetamide 

      Davis, Rohan; Healy, Peter; Poulsen, Sally-Ann (Acta Crystallographica. Section E: Structure reports online, 2007)
      The crystal structure of the title sulfonamide, C16H18N2O4S, is stabilized by strong N-H...O and O-H...O intermolecular hydrogen bonds.
      JOURNAL ARTICLE
    • N.M.R. studies of some chromium(III) dithiocarbamate complexes 

      Golding, R.; Healy, P.; Colombera, P.; White, A. (Australian Journal of Chemistry, 1974)
      The temperature dependence of the proton N.M.R. spectra of some simple tris(N,N-disubstituted dithiocarbamato)chromium(111) derivatives, [Cr(S2CNR2)3], has been studied in deuterochloroform solution over the range ? 60꠴o ...
      JOURNAL ARTICLE
    • N.N'-Ethylenedisuccinimide 

      Brown, Chris; Head, Sarah; Healy, Peter (Acta crystallographica. Section E, Structure reports online, 2005)
      The title compound, C10H12N2O4, crystallizes as discrete molecules disposed about crystallographic centres of symmetry, with two independent half-molecules constituting the asymmetric unit of the unit cell. The succinimide ...
      JOURNAL ARTICLE
    • Na+-H+ Exchanger Regulatory Factor 1 (NHERF1) PDZ Scaffold Binds an Internal Binding Site in the Scavenger Receptor Megalin 

      Slattery, Craig; Jenkin, Kayte A.; Lee, Aven; Simcocks, Anna; McAinch, Andrew J.; Poronnik, Philip; Hryciw, Deanne (Cellular Physiology and Biochemistry, 2011)
      The scavenger receptor megalin binds to albumin in the microvilli of the renal proximal tubule, and transports the ligand to the intravillar cleft for processing by endocytosis. Albumin endocytosis in the proximal tubule ...
      JOURNAL ARTICLE