Quetiapine adverse events in older adults in Australia
Author(s)
El-Saifi, Najwan
Jones, Cindy
Moyle, Wendy
Griffith University Author(s)
Year published
2016
Metadata
Show full item recordAbstract
Aim: To characterise quetiapine reported adverse drug
events (ADEs) in older Australians in terms of type,
frequency, severity and outcome, and to compare these
characteristics with those of younger Australians.
Methods: Basic descriptive analyses were used to examine
patient characteristics. The characteristics of reported
ADEs were compared between older and younger
Australians using odds ratios and chi-squared tests.
Results: The most frequently reported ADEs in older
people were nervous system disorders (23.7%). There were
significantly more reports of skin and subcutaneous ADEs
and hepatobiliary ADEs for older people ...
View more >Aim: To characterise quetiapine reported adverse drug events (ADEs) in older Australians in terms of type, frequency, severity and outcome, and to compare these characteristics with those of younger Australians. Methods: Basic descriptive analyses were used to examine patient characteristics. The characteristics of reported ADEs were compared between older and younger Australians using odds ratios and chi-squared tests. Results: The most frequently reported ADEs in older people were nervous system disorders (23.7%). There were significantly more reports of skin and subcutaneous ADEs and hepatobiliary ADEs for older people than for younger people. More severe ADEs were reported in older people with death more likely to occur in older than in younger people Conclusion: Significant differences between older and younger people in terms of reported ADEs, severity and mortality were found. There is a need for further prospective studies in older people on quetiapine to confirm the findings of this study
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View more >Aim: To characterise quetiapine reported adverse drug events (ADEs) in older Australians in terms of type, frequency, severity and outcome, and to compare these characteristics with those of younger Australians. Methods: Basic descriptive analyses were used to examine patient characteristics. The characteristics of reported ADEs were compared between older and younger Australians using odds ratios and chi-squared tests. Results: The most frequently reported ADEs in older people were nervous system disorders (23.7%). There were significantly more reports of skin and subcutaneous ADEs and hepatobiliary ADEs for older people than for younger people. More severe ADEs were reported in older people with death more likely to occur in older than in younger people Conclusion: Significant differences between older and younger people in terms of reported ADEs, severity and mortality were found. There is a need for further prospective studies in older people on quetiapine to confirm the findings of this study
View less >
Journal Title
Australasian Journal on Ageing
Note
This publication has been entered into Griffith Research Online as an Advanced Online Version.
Subject
Biomedical and clinical sciences
Human society
Other human society not elsewhere classified
Psychology