dc.contributor.author | Chakraborti, Asit K | |
dc.contributor.author | Rudrawar, Santosh | |
dc.contributor.author | Jadhav, Kirtikumar B | |
dc.contributor.author | Kaur, Gurmeet | |
dc.contributor.author | Chankeshwara, Sunay V | |
dc.date.accessioned | 2018-11-05T00:07:59Z | |
dc.date.available | 2018-11-05T00:07:59Z | |
dc.date.issued | 2007 | |
dc.identifier.issn | 1463-9262 | |
dc.identifier.doi | 10.1039/B710414F | |
dc.identifier.uri | http://hdl.handle.net/10072/100273 | |
dc.description.abstract | A convenient and clean “on water”-mediated synthesis of benzothiazoles/benzothiazolines is reported. Aromatic, heteroaromatic, and styryl aldehydes are converted to 2-substituted benzothiazoles in high yields in a one-pot reaction with 2-aminothiophenol in water at 110 °C (oil-bath). Alkyl and aryl alkyl aldehydes afforded the benzothiazolines. The reaction is highly chemoselective with no competitive thia-Michael addition, O-dealkylation/debenzoylation, reduction of the nitro or the α,β-unsaturated carbonyl groups, and substitution of the halogen atom or the nitro group. The reaction is found to be general with respect to the 2-aminothiophenol substrate through the reaction of a few substituted 2-aminothiophenols with a few representative aromatic and aliphatic aldehydes. The procedure does not involve the use of any additional reagent/catalyst, produces no waste, and represents a green synthetic protocol. | |
dc.description.peerreviewed | Yes | |
dc.language | English | |
dc.language.iso | eng | |
dc.publisher | Royal Society of Chemistry | |
dc.relation.ispartofpagefrom | 1335 | |
dc.relation.ispartofpageto | 1340 | |
dc.relation.ispartofissue | 12 | |
dc.relation.ispartofjournal | Green Chemistry | |
dc.relation.ispartofvolume | 9 | |
dc.subject.fieldofresearch | Chemical sciences | |
dc.subject.fieldofresearch | Other chemical sciences not elsewhere classified | |
dc.subject.fieldofresearchcode | 34 | |
dc.subject.fieldofresearchcode | 349999 | |
dc.title | “On water” organic synthesis: a highly efficient and clean synthesis of 2-aryl/heteroaryl/styryl benzothiazoles and 2-alkyl/aryl alkyl benzothiazolines | |
dc.type | Journal article | |
dc.type.description | C1 - Articles | |
dc.type.code | C - Journal Articles | |
gro.hasfulltext | No Full Text | |
gro.griffith.author | Rudrawar, Santosh | |