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dc.contributor.authorAlayan, Jamil
dc.contributor.authorVaquette, Cedryck
dc.contributor.authorFarah, Camile
dc.contributor.authorIvanovski, Saso
dc.date.accessioned2018-07-18T03:13:02Z
dc.date.available2018-07-18T03:13:02Z
dc.date.issued2016
dc.identifier.issn0905-7161
dc.identifier.doi10.1111/clr.12694
dc.identifier.urihttp://hdl.handle.net/10072/100523
dc.description.abstractObjective: To histomorphometrically compare the use of collagen-stabilized anorganic bovine bone (ABBM-C) (test) to anorganic bovine bone + autogenous bone (ABBM + AB) (control) in maxillary sinus augmentation. Materials and Methods: Forty (n = 40 sinuses) patients underwent sinus augmentation and received either control (20 sinuses) or test bone graft (20 sinuses). Bone samples were harvested from the augmented sinuses 5 months postgrafting. The samples were processed for histomorphometry, which assessed within the primary region of interest (ROI-1), the area fraction of new bone (%NB), graft particle osseointegration (% OI), residual graft (%RG), and soft tissue components (% STM). The same analysis was also carried out in a second region of interest (ROI-2) located in a zone 1 mm proximal to the previous maxillary sinus floor. Results: In both ROI-1 and ROI-2, the mean % NB, %RG, and %STM in the control group were similar to mean values in the test group. The % OI was significantly greater in the control group (42.0 +/− 26.8) when compared to the test group (19.6 +/− 27.3) in ROI-2 (P < 0.05). No statistically significant differences were seen when ROI-1 and ROI-2 were compared except for improved %OI in ROI-2 in the control group. The mean proportion of lamellar bone to woven bone in the control group (1.22 ± 1.48) was significantly greater than the test group (0.38 ± 0.29) (P < 0.05). Conclusion: ABBM-C exhibited very similar histomorphometric parameters to the composite graft of ABBM + AB. The ABBM + AB group was more mature as indicated by the significantly greater proportion of lamellar bone when compared to the ABBM-C. Improved % OI was seen in the zone proximal to the resident bony floor in the ABBM + AB group. Based on histological assessment, ABBM-C is a suitable bone substitute for the purposes of maxillary sinus augmentation. Its clinical utility may be indicated in cases of sinus membrane perforation and insufficient autogenous bone in the local area.
dc.description.peerreviewedYes
dc.languageEnglish
dc.publisherWiley-Blackwell Publishing
dc.relation.ispartofpagefrom850
dc.relation.ispartofpageto858
dc.relation.ispartofissue7
dc.relation.ispartofjournalClinical Oral Implants Research
dc.relation.ispartofvolume27
dc.subject.fieldofresearchBiomedical engineering
dc.subject.fieldofresearchBiomedical engineering not elsewhere classified
dc.subject.fieldofresearchDentistry
dc.subject.fieldofresearchcode4003
dc.subject.fieldofresearchcode400399
dc.subject.fieldofresearchcode3203
dc.titleA histomorphometric assessment of collagen-stabilized anorganic bovine bone mineral in maxillary sinus augmentation - a prospective clinical trial
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.facultyGriffith Health, School of Dentistry and Oral Health
gro.hasfulltextNo Full Text
gro.griffith.authorIvanovski, Saso
gro.griffith.authorAlayan, Jamil
gro.griffith.authorVaquette, Cedryck


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