dc.contributor.author | Alayan, Jamil | |
dc.contributor.author | Vaquette, Cedryck | |
dc.contributor.author | Farah, Camile | |
dc.contributor.author | Ivanovski, Saso | |
dc.date.accessioned | 2018-07-18T03:13:02Z | |
dc.date.available | 2018-07-18T03:13:02Z | |
dc.date.issued | 2016 | |
dc.identifier.issn | 0905-7161 | |
dc.identifier.doi | 10.1111/clr.12694 | |
dc.identifier.uri | http://hdl.handle.net/10072/100523 | |
dc.description.abstract | Objective: To histomorphometrically compare the use of collagen-stabilized anorganic bovine bone (ABBM-C) (test) to anorganic bovine bone + autogenous bone (ABBM + AB) (control) in maxillary sinus augmentation.
Materials and Methods: Forty (n = 40 sinuses) patients underwent sinus augmentation and received either control (20 sinuses) or test bone graft (20 sinuses). Bone samples were harvested from the augmented sinuses 5 months postgrafting. The samples were processed for histomorphometry, which assessed within the primary region of interest (ROI-1), the area fraction of new bone (%NB), graft particle osseointegration (% OI), residual graft (%RG), and soft tissue components (% STM). The same analysis was also carried out in a second region of interest (ROI-2) located in a zone 1 mm proximal to the previous maxillary sinus floor.
Results: In both ROI-1 and ROI-2, the mean % NB, %RG, and %STM in the control group were similar to mean values in the test group. The % OI was significantly greater in the control group (42.0 +/− 26.8) when compared to the test group (19.6 +/− 27.3) in ROI-2 (P < 0.05). No statistically significant differences were seen when ROI-1 and ROI-2 were compared except for improved %OI in ROI-2 in the control group. The mean proportion of lamellar bone to woven bone in the control group (1.22 ± 1.48) was significantly greater than the test group (0.38 ± 0.29) (P < 0.05).
Conclusion: ABBM-C exhibited very similar histomorphometric parameters to the composite graft of ABBM + AB. The ABBM + AB group was more mature as indicated by the significantly greater proportion of lamellar bone when compared to the ABBM-C. Improved % OI was seen in the zone proximal to the resident bony floor in the ABBM + AB group. Based on histological assessment, ABBM-C is a suitable bone substitute for the purposes of maxillary sinus augmentation. Its clinical utility may be indicated in cases of sinus membrane perforation and insufficient autogenous bone in the local area. | |
dc.description.peerreviewed | Yes | |
dc.language | English | |
dc.publisher | Wiley-Blackwell Publishing | |
dc.relation.ispartofpagefrom | 850 | |
dc.relation.ispartofpageto | 858 | |
dc.relation.ispartofissue | 7 | |
dc.relation.ispartofjournal | Clinical Oral Implants Research | |
dc.relation.ispartofvolume | 27 | |
dc.subject.fieldofresearch | Biomedical engineering | |
dc.subject.fieldofresearch | Biomedical engineering not elsewhere classified | |
dc.subject.fieldofresearch | Dentistry | |
dc.subject.fieldofresearchcode | 4003 | |
dc.subject.fieldofresearchcode | 400399 | |
dc.subject.fieldofresearchcode | 3203 | |
dc.title | A histomorphometric assessment of collagen-stabilized anorganic bovine bone mineral in maxillary sinus augmentation - a prospective clinical trial | |
dc.type | Journal article | |
dc.type.description | C1 - Articles | |
dc.type.code | C - Journal Articles | |
gro.faculty | Griffith Health, School of Dentistry and Oral Health | |
gro.hasfulltext | No Full Text | |
gro.griffith.author | Ivanovski, Saso | |
gro.griffith.author | Alayan, Jamil | |
gro.griffith.author | Vaquette, Cedryck | |