Macrolactam analogues of macrolide natural products

Author(s)
Hugel, Helmut M
Smith, Andrew T
Rizzacasa, Mark A
Griffith University Author(s)
Year published
2016
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Abstract
The chemical modification of macrolide natural products into aza- or lactam analogues is a strategy employed to improve their metabolic stability and biological activity. The methods for the synthesis of several lactam analogues of macrolide natural products are highlighted and aspects of their biological properties presented.
Journal Title
Organic & Biomolecular Chemistry
Volume
14
DOI
Subject
Medicinal and biomolecular chemistry
Medicinal and biomolecular chemistry not elsewhere classified
Organic chemistry
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