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dc.contributor.authorRigney, Louise
dc.contributor.authorCappelen-Smith, Cecilia
dc.contributor.authorSebire, Dale
dc.contributor.authorBeran, Roy
dc.contributor.authorCordato, Dennis
dc.date.accessioned2018-10-08T04:21:01Z
dc.date.available2018-10-08T04:21:01Z
dc.date.issued2015
dc.identifier.issn0967-5868en_US
dc.identifier.doi10.1016/j.jocn.2015.03.037en_US
dc.identifier.urihttp://hdl.handle.net/10072/101625
dc.description.abstractThis study presents the clinical features and functional outcomes of eight consecutive patients who were admitted to our institution between 2012 and 2014 with nontraumatic spinal cord infarction (SCI), a rare and devastating condition. We also present a literature review of aetiologies and prognostic factors relevant to our case series. The mean age of our cohort was 64 years and five patients were female. Aortic disease was causative in three, including one patient with biopsy confirmed giant cell arteritis. Fibrocartilaginous embolism was a possible aetiology in two others, anterior spinal artery aneurysm in one, and the cause was undetermined in two patients. American Spinal Injury Association impairment scale (ASIA) scores at nadir (time of maximum severity of signs) were B in three, C in three and D in two patients (all were wheelchair dependent). At last follow-up, ASIA scores were C in one, D in five and E in one patient. One patient died, two remained wheelchair dependent, four required a walking aid or frame and one was mobilising independently. A literature review of 11 patient series of nontraumatic SCI found that prognosis is primarily determined by the severity of motor or sensory involvement, in particular, initial and nadir ASIA A/B scores which strongly correlate with poor outcome. In the majority of series, 40–60% of patients had initial ASIA A/B scores with a similar proportion remaining wheelchair dependent on follow-up. Most patients in our cohort had nadir ASIA C/D scores, which may explain their better outcomes.en_US
dc.description.peerreviewedYesen_US
dc.languageEnglishen_US
dc.publisherChurchill Livingstoneen_US
dc.relation.ispartofpagefrom1544en_US
dc.relation.ispartofpageto1549en_US
dc.relation.ispartofissue10en_US
dc.relation.ispartofjournalJournal of Clinical Neuroscienceen_US
dc.relation.ispartofvolume22en_US
dc.subject.fieldofresearchNeurosciences not elsewhere classifieden_US
dc.subject.fieldofresearchcode110999en_US
dc.titleNontraumatic spinal cord ischaemic syndromeen_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Peer Reviewed (HERDC)en_US
dc.type.codeC - Journal Articlesen_US
gro.hasfulltextNo Full Text


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