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  • The nature of prospective memory deficit in patients with obsessive-compulsive disorder

    Author(s)
    Yang, Tian-xiao
    Peng, Zi-wen
    Wang, Ya
    Geng, Fu-lei
    Miao, Guo-dong
    Shum, David HK
    Cheung, Eric FC
    Chan, Raymond CK
    Griffith University Author(s)
    Shum, David
    Chan, Raymond
    Year published
    2015
    Metadata
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    Abstract
    We comprehensively examined prospective memory (PM) performance in patients with obsessive–compulsive disorder (OCD), and explored the cognitive and psychopathological correlates of PM in this clinical population. Fifty-eight OCD patients and 58 healthy controls were assessed with computer-based PM tasks and related neurocognitive functions, and the participants also reported frequency of PM failures and compulsive behaviours in daily life. OCD patients had intact activity-based PM performance but had lower accuracy in time-based PM and longer reaction time to event-based PM cues compared to healthy controls. Among the ...
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    We comprehensively examined prospective memory (PM) performance in patients with obsessive–compulsive disorder (OCD), and explored the cognitive and psychopathological correlates of PM in this clinical population. Fifty-eight OCD patients and 58 healthy controls were assessed with computer-based PM tasks and related neurocognitive functions, and the participants also reported frequency of PM failures and compulsive behaviours in daily life. OCD patients had intact activity-based PM performance but had lower accuracy in time-based PM and longer reaction time to event-based PM cues compared to healthy controls. Among the neurocognitive functions, both the WCST (perseverative error) and the letter number span correlated with time-based PM. OCD patients reported similar number of PM failures in daily life as controls, which correlated with their intact event-based PM performance, suggesting a generally good insight into their PM functions. Neither clinician-assessed nor self-reported OCD symptoms correlated with PM performance. This study indicates that PM impairment tends to vary with the PM cue types in OCD patients. In addition, certain executive functions (i.e., mental shifting and updating) may contribute to time-based PM impairment in patients with OCD.
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    Journal Title
    Psychiatry Research
    Volume
    230
    Issue
    2
    DOI
    https://doi.org/10.1016/j.psychres.2015.09.041
    Subject
    Biomedical and clinical sciences
    Psychology
    Other psychology not elsewhere classified
    Publication URI
    http://hdl.handle.net/10072/101746
    Collection
    • Journal articles

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