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dc.contributor.authorFreschi, Lucaen_US
dc.contributor.authorJeukens, Julieen_US
dc.contributor.authorKukavica-Ibrulj, Irenaen_US
dc.contributor.authorBoyle, Brianen_US
dc.contributor.authorDupont, Marie-Joseeen_US
dc.contributor.authorLaroche, Jeromeen_US
dc.contributor.authorLarose, Stephaneen_US
dc.contributor.authorMaaroufi, Halimen_US
dc.contributor.authorFothergill, Joanne L.en_US
dc.contributor.authorMoore, Matthewen_US
dc.contributor.authorWinsor, Geoffrey L.en_US
dc.contributor.authorAaron, Shawn D.en_US
dc.contributor.authorBarbeau, Jeanen_US
dc.contributor.authorBell, Scott C.en_US
dc.contributor.authorBurns, Jane L.en_US
dc.contributor.authorCamara, Miguelen_US
dc.contributor.authorCantin, Andréen_US
dc.contributor.authorCharette, Steve J.en_US
dc.contributor.authorDewar, Kenen_US
dc.contributor.authorDeziel, Ericen_US
dc.contributor.authorGrimwood, Keithen_US
dc.contributor.authorHancock, Robert E.en_US
dc.contributor.authorHarrison, Joe J.en_US
dc.contributor.authorHeeb, Stephenen_US
dc.contributor.authorJelsbak, Larsen_US
dc.contributor.authorJia, Baofengen_US
dc.contributor.authorKenna, Dervla T.en_US
dc.contributor.authorKidd, Timothy J.en_US
dc.contributor.authorKlockgether, Jensen_US
dc.contributor.authorLam, Josephen_US
dc.contributor.authorLamont, Iain L.en_US
dc.contributor.authorLewenza, Shawnen_US
dc.contributor.authorLoman, Nicken_US
dc.contributor.authorMalouin, Francoisen_US
dc.contributor.authorManos, Jimen_US
dc.contributor.authorMcArthur, Andrew G.en_US
dc.contributor.authorMcKeown, Josieen_US
dc.contributor.authorMilot, Julieen_US
dc.contributor.authorNaghra, Hardeepen_US
dc.contributor.authorNguyen, Daoen_US
dc.contributor.authorPereira, Sheldon K.en_US
dc.contributor.authorPerron, Gabriel G.en_US
dc.contributor.authorPirnay, Jean-Paulen_US
dc.contributor.authorRainey, Paul B.en_US
dc.contributor.authorRousseau, Simonen_US
dc.contributor.authorSantos, Pedro M.en_US
dc.contributor.authorStephenson, Anneen_US
dc.contributor.authorTaylor, Veroniqueen_US
dc.contributor.authorTurton, Jane F.en_US
dc.contributor.authorWaglechner, Nicholasen_US
dc.contributor.authorWilliams, Paulen_US
dc.contributor.authorThrane, Sandra W.en_US
dc.contributor.authorWright, Gerard D.en_US
dc.contributor.authorS. L. Brinkman, Fionaen_US
dc.contributor.authorTucker, Nicholas P.en_US
dc.contributor.authorTummler, Burkharden_US
dc.contributor.authorWinstanley, Craigen_US
dc.contributor.authorLevesque, Roger C.en_US
dc.date.accessioned2017-08-30T05:00:43Z
dc.date.available2017-08-30T05:00:43Z
dc.date.issued2015en_US
dc.identifier.issn1664-302Xen_US
dc.identifier.doi10.3389/fmicb.2015.01036en_US
dc.identifier.urihttp://hdl.handle.net/10072/101852
dc.description.abstractThe International Pseudomonas aeruginosa Consortium is sequencing over 1000 genomes and building an analysis pipeline for the study of Pseudomonas genome evolution, antibiotic resistance and virulence genes. Metadata, including genomic and phenotypic data for each isolate of the collection, are available through the International Pseudomonas Consortium Database (http://ipcd.ibis.ulaval.ca/). Here, we present our strategy and the results that emerged from the analysis of the first 389 genomes. With as yet unmatched resolution, our results confirm that P. aeruginosa strains can be divided into three major groups that are further divided into subgroups, some not previously reported in the literature. We also provide the first snapshot of P. aeruginosa strain diversity with respect to antibiotic resistance. Our approach will allow us to draw potential links between environmental strains and those implicated in human and animal infections, understand how patients become infected and how the infection evolves over time as well as identify prognostic markers for better evidence-based decisions on patient care.en_US
dc.description.peerreviewedYesen_US
dc.languageEnglishen_US
dc.publisherFrontiers Research Foundationen_US
dc.relation.ispartofpagefrom1036-1en_US
dc.relation.ispartofpageto1036-8en_US
dc.relation.ispartofjournalFrontiers in Microbiologyen_US
dc.relation.ispartofvolume6en_US
dc.subject.fieldofresearchMicrobiology not elsewhere classifieden_US
dc.subject.fieldofresearchcode060599en_US
dc.titleClinical utilization of genomics data produced by the international Pseudomonas aeruginosa consortiumen_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Peer Reviewed (HERDC)en_US
dc.type.codeC - Journal Articlesen_US
dcterms.licensehttps://creativecommons.org/licenses/by/4.0/en_US
dc.description.versionPublisheden_US
gro.rights.copyright© 2015 Freschi, Jeukens, Kukavica-Ibrulj, Boyle, Dupont, Laroche, Larose, Maaroufi, Fothergill, Moore, Winsor, Aaron, Barbeau, Bell, Burns, Camara, Cantin, Charette, Dewar, Déziel, Grimwood, Hancock, Harrison, Heeb, Jelsbak, Jia, Kenna, Kidd, Klockgether, Lam, Lamont, Lewenza, Loman, Malouin, Manos, McArthur, McKeown, Milot, Naghra, Nguyen, Pereira, Perron, Pirnay, Rainey, Rousseau, Santos, Stephenson, Taylor, Turton, Waglechner, Williams, Thrane, Wright, Brinkman, Tucker, Tümmler, Winstanley and Levesque. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.en_US
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