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dc.contributor.authorBoyd, Roslyn N
dc.contributor.authorBaque, Emmah
dc.contributor.authorPiovesana, Adina
dc.contributor.authorRoss, Stephanie
dc.contributor.authorZiviani, Jenny
dc.contributor.authorSakzewski, Leanne
dc.contributor.authorBarber, Lee
dc.contributor.authorLloyd, Owen
dc.contributor.authorMcKinlay, Lynne
dc.contributor.authorWhittingham, Koa
dc.contributor.authorSmith, Anthony C
dc.contributor.authorRose, Stephen
dc.contributor.authorFiori, Simona
dc.contributor.authorCunnington, Ross
dc.contributor.authorWare, Robert
dc.contributor.authorLewis, Melinda
dc.contributor.authorComans, Tracy A
dc.contributor.authorScuffham, Paul A
dc.date.accessioned2017-08-06T22:46:16Z
dc.date.available2017-08-06T22:46:16Z
dc.date.issued2015
dc.identifier.issn1471-2377
dc.identifier.doi10.1186/s12883-015-0381-6
dc.identifier.urihttp://hdl.handle.net/10072/102518
dc.description.abstractBackground: Acquired brain injury (ABI) refers to multiple disabilities arising from damage to the brain acquired after birth. Children with an ABI may experience physical, cognitive, social and emotional-behavioural impairments which can impact their ability to participate in activities of daily living (ADL). Recent developments in technology have led to the emergence of internet-delivered therapy programs. “Move it to improve it” (Mitii™) is a web-based multi-modal therapy that comprises upper limb (UL) and cognitive training within the context of meaningful physical activity. The proposed study aims to compare the efficacy of Mitii™ to usual care to improve ADL motor and processing skills, gross motor capacity, UL and executive functioning in a randomised waitlist controlled trial. Methods/Design: Sixty independently ambulant children (30 in each group) at least 12 months post ABI will be recruited to participate in this trial. Children will be matched in pairs at baseline and randomly allocated to receive either 20 weeks of Mitii™ training (30 min per day, six days a week, with a potential total dose of 60 h) immediately, or be waitlisted for 20 weeks. Outcomes will be assessed at baseline, immediately post-intervention and at 20 weeks post-intervention. The primary outcomes will be the Assessment of Motor and Process Skills and 30 s repetition maximum of functional strength exercises (sit-to-stand, step-ups and half kneel to stand). Measures of body structure and functions, activity, participation and quality of life will assess the efficacy of Mitii™ across all domains of the International Classification of Functioning, Disability and Health framework. A subset of children will undertake three tesla (3T) magnetic resonance imaging scans to evaluate functional neurovascular changes, structural imaging, diffusion imaging and resting state functional connectivity before and after intervention. Discussion: Mitii™ provides an alternative approach to deliver intensive therapy for children with an ABI in the convenience of the home environment. If Mitii™ is found to be effective, it may offer an accessible and inexpensive intervention option to increase therapy dose.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherBioMed Central
dc.publisher.placeUnited Kingdom
dc.relation.ispartofpagefrom140-1
dc.relation.ispartofpageto140-29
dc.relation.ispartofjournalBMC Neurology
dc.relation.ispartofvolume15
dc.subject.fieldofresearchNeurosciences not elsewhere classified
dc.subject.fieldofresearchNeurosciences
dc.subject.fieldofresearchCognitive Sciences
dc.subject.fieldofresearchcode110999
dc.subject.fieldofresearchcode1109
dc.subject.fieldofresearchcode1702
dc.titleMitii™ ABI: Study protocol of a randomised controlled trial of a web-based multi-modal training program for children and adolescents with an Acquired Brain Injury (ABI)
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
dcterms.licensehttp://creativecommons.org/licenses/by/4.0/
dc.description.versionVersion of Record (VoR)
gro.rights.copyright© Boyd et al. 2015. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
gro.hasfulltextFull Text
gro.griffith.authorScuffham, Paul A.
gro.griffith.authorComans, Tracy
gro.griffith.authorWare, Robert
gro.griffith.authorBaque, Emmah
gro.griffith.authorLloyd, Owen T.
gro.griffith.authorBarber, Lee A.


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