dc.contributor.author | BERNERSPRICE, SJ | |
dc.contributor.author | RANFORD, JD | |
dc.contributor.author | SADLER, PJ | |
dc.date.accessioned | 2017-09-22T00:06:22Z | |
dc.date.available | 2017-09-22T00:06:22Z | |
dc.date.issued | 1994 | |
dc.identifier.issn | 0020-1669 | |
dc.identifier.doi | 10.1021/ic00103a036 | |
dc.identifier.uri | http://hdl.handle.net/10072/118245 | |
dc.description.abstract | We report studies of the pH and temperature dependences of N-H NMR resonances of [Pt(15N-en){d(GpG)N7(1 ),N7(2)} ]2+ (1), [Pt(15N-en){ d(pGpG)-N7(1 ),N7(2)} ]2+ (2), and [Pt(15N-en){ d(TpGpG)-N7(2),N7(3)} ]2+ (3) in aqueous solution using 15N-edited 1H and [1H, 15N1 heteronuclear multiple quantum coherence (HMQC) 2D NMR spectroscopy. The data for 2 are consistent with strong stereospecific intramolecular H bonding involving only one of the en NH hydrogens and the deprotonated dianionic terminal 5'-phosphate group, for which the pKa is lowered by ca. 0.5 units to 6.46. The NMR data for complex 1 are similar to those of complex 3, suggesting either that such H bonding is very weak for a bridging monoanionic 5'-phosphate (diester) or, more likely, that these NMR methods are insensitive to its presence. | |
dc.description.peerreviewed | Yes | |
dc.language | English | |
dc.language.iso | eng | |
dc.publisher | American Chemical Society | |
dc.publisher.place | USA | |
dc.relation.ispartofpagefrom | 5842 | |
dc.relation.ispartofpageto | 5846 | |
dc.relation.ispartofjournal | Inorganic Chemistry | |
dc.relation.ispartofvolume | 33 | |
dc.subject.fieldofresearch | Chemical sciences | |
dc.subject.fieldofresearch | Inorganic chemistry | |
dc.subject.fieldofresearch | Physical chemistry | |
dc.subject.fieldofresearch | Other chemical sciences | |
dc.subject.fieldofresearchcode | 34 | |
dc.subject.fieldofresearchcode | 3402 | |
dc.subject.fieldofresearchcode | 3406 | |
dc.subject.fieldofresearchcode | 3499 | |
dc.title | [1H, 15N] NMR Investigations of Pt-NH Hydrogen Bonding in d(GpG), d(pGpG), and d(TpGpG)-N7,N7 Adducts of [Pt(en)]2+ in Aqueous Solution | |
dc.type | Journal article | |
dc.type.description | C1 - Articles | |
dc.type.code | C - Journal Articles | |
gro.faculty | Office of the Snr Dep Vice Chancellor, Institute for Glycomics | |
gro.hasfulltext | No Full Text | |
gro.griffith.author | Berners-Price, Sue J. | |