dc.contributor.author | Redburn, Joanne | |
dc.contributor.author | Leah, John | |
dc.date.accessioned | 2019-05-26T22:24:01Z | |
dc.date.available | 2019-05-26T22:24:01Z | |
dc.date.issued | 1997 | |
dc.identifier.issn | 03043940 | |
dc.identifier.doi | 10.1016/S0304-3940(97)00820-3 | |
dc.identifier.uri | http://hdl.handle.net/10072/120995 | |
dc.description.abstract | c-Fos expression was examined in rat brains at increasing times after a single noxious stimulus to one hindpaw. In some nuclei the expression peaked at 1 h and was gone by 6 h; in others it was biphasic with a larger peak appearing 6 h after the first. In other rats a second, contralateral stimulus was given at increasing times after the first, and c-Fos examined after a further 1.5 h. In some nuclei the first stimulus potentiated c-Fos expression caused by the second stimulus; in others the second stimulus erased any c-Fos still present from the first. Thus two similar stimuli can interact in very different ways in effecting c-Fos expression in different central nervous system nuclei, and rapid down-regulation might represent a novel type of interaction. | |
dc.description.peerreviewed | Yes | |
dc.language | English | |
dc.language.iso | eng | |
dc.publisher | Elsevier Science | |
dc.publisher.place | Ireland | |
dc.relation.ispartofpagefrom | 97 | |
dc.relation.ispartofpageto | 100 | |
dc.relation.ispartofissue | 2-3 | |
dc.relation.ispartofjournal | Neuroscience Letters | |
dc.relation.ispartofvolume | 237 | |
dc.subject.fieldofresearch | Neurosciences | |
dc.subject.fieldofresearch | Psychology | |
dc.subject.fieldofresearch | Cognitive Sciences | |
dc.subject.fieldofresearchcode | 1109 | |
dc.subject.fieldofresearchcode | 1701 | |
dc.subject.fieldofresearchcode | 1702 | |
dc.title | Accelerated Breakdown and Enhanced Expression of c-Fos in the Rat Brain after Noxious Stimulation | |
dc.type | Journal article | |
dc.type.description | C1 - Articles | |
dc.type.code | C - Journal Articles | |
gro.faculty | Griffith Sciences, Griffith Institute for Drug Discovery | |
gro.hasfulltext | No Full Text | |
gro.griffith.author | Leah, John D. | |
gro.griffith.author | Redburn, Joanne | |