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  • High performance liquid chromatography determined alkamide levels in Australian-grown Echinacea spp

    Author(s)
    Rogers, KL
    Grice, ID
    Mitchell, CJ
    Griffiths, LR
    Griffith University Author(s)
    Grice, Darren D.
    Griffiths, Lyn
    Mitchell, Christopher
    Rogers, Kelly
    Year published
    1998
    Metadata
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    Abstract
    Extracts of Echinacea spp. are widely used as therapeutic immunostimulants with such activity being attributed in part to the alkamide fractions of these plants. Using high performance liquid chromatography, the levels of 8 alkamides, including 2 tetraene alkamides (dodeca-2E, 4E, 8Z, 10E/Z-tetraenoic acid isobutylamide), were quantitatively determined in 2 Australian-grown Echinacea spp. Overall, the levels of alkamides in Australian-grown E. angustifolia were found to be comparable with levels obtained in this study and other studies for USA and European Echinacea spp. However, results obtained for one sample of E. ...
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    Extracts of Echinacea spp. are widely used as therapeutic immunostimulants with such activity being attributed in part to the alkamide fractions of these plants. Using high performance liquid chromatography, the levels of 8 alkamides, including 2 tetraene alkamides (dodeca-2E, 4E, 8Z, 10E/Z-tetraenoic acid isobutylamide), were quantitatively determined in 2 Australian-grown Echinacea spp. Overall, the levels of alkamides in Australian-grown E. angustifolia were found to be comparable with levels obtained in this study and other studies for USA and European Echinacea spp. However, results obtained for one sample of E. angustifolia suggested that it may have been mislabelled and that it was most likely a sample of E. pallida. Levels of tetraene alkamides in Australian-grown E. purpurea were also similar to, if not higher, than levels which have been reported for the same species grown in Germany and the USA. Preliminary studies on the stability of alkamide compounds in E. angustifolia indicated that they are susceptible to degradation, with a 13% loss of alkamide level over 2 months. Overall, results indicate that there is considerable potential to develop Echinacea as a viable crop in Australia.
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    Journal Title
    Australian Journal of Experimental Agriculture
    Volume
    38
    Issue
    4
    DOI
    https://doi.org/10.1071/EA98001
    Subject
    Environmental sciences
    Biological sciences
    Agricultural, veterinary and food sciences
    Publication URI
    http://hdl.handle.net/10072/122088
    Collection
    • Journal articles

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