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  • Isolation of Xestosterol Esters of Brominated Acetylenic Fatty Acids from the Marine Sponge Xestospongia testudinaria

    Author(s)
    Pham, NB
    Butler, MS
    Hooper, JNA
    Moni, RW
    Quinn, RJ
    Griffith University Author(s)
    Quinn, Ronald J.
    Moni, Roger W.
    Butler, Mark S.
    Pham, Ngoc B.
    Hooper, John N.
    Year published
    1999
    Metadata
    Show full item record
    Abstract
    The CH2Cl2 extract of the marine sponge Xestospongia testudinaria inhibited [3H]DPCPX binding to rat-brain adenosine A1 receptors. Bioassay-guided fractionation led to the isolation of a known brominated acetylenic fatty acid 1 as the active component. Also isolated were two novel sterol esters 2 and 3. All structures were determined on the basis of their spectroscopic data.The CH2Cl2 extract of the marine sponge Xestospongia testudinaria inhibited [3H]DPCPX binding to rat-brain adenosine A1 receptors. Bioassay-guided fractionation led to the isolation of a known brominated acetylenic fatty acid 1 as the active component. Also isolated were two novel sterol esters 2 and 3. All structures were determined on the basis of their spectroscopic data.
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    Journal Title
    Journal of Natural Products
    Volume
    62
    Issue
    10
    DOI
    https://doi.org/10.1021/np9901635
    Subject
    Chemical sciences
    Biological sciences
    Biomedical and clinical sciences
    Publication URI
    http://hdl.handle.net/10072/122366
    Collection
    • Journal articles

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