Isolation of Xestosterol Esters of Brominated Acetylenic Fatty Acids from the Marine Sponge Xestospongia testudinaria
Author(s)
Pham, NB
Butler, MS
Hooper, JNA
Moni, RW
Quinn, RJ
Griffith University Author(s)
Year published
1999
Metadata
Show full item recordAbstract
The CH2Cl2 extract of the marine sponge Xestospongia testudinaria inhibited [3H]DPCPX binding to rat-brain adenosine A1 receptors. Bioassay-guided fractionation led to the isolation of a known brominated acetylenic fatty acid 1 as the active component. Also isolated were two novel sterol esters 2 and 3. All structures were determined on the basis of their spectroscopic data.The CH2Cl2 extract of the marine sponge Xestospongia testudinaria inhibited [3H]DPCPX binding to rat-brain adenosine A1 receptors. Bioassay-guided fractionation led to the isolation of a known brominated acetylenic fatty acid 1 as the active component. Also isolated were two novel sterol esters 2 and 3. All structures were determined on the basis of their spectroscopic data.
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Journal Title
Journal of Natural Products
Volume
62
Issue
10
Subject
Chemical sciences
Biological sciences
Biomedical and clinical sciences