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dc.contributor.authorConnell, DW
dc.contributor.authorChaisuksant, Y
dc.contributor.authorYu, J
dc.date.accessioned2020-02-27T06:31:10Z
dc.date.available2020-02-27T06:31:10Z
dc.date.issued1999
dc.identifier.issn0025-326X
dc.identifier.doi10.1016/S0025-326X(99)00084-3
dc.identifier.urihttp://hdl.handle.net/10072/122392
dc.description.abstractEcological risk evaluations are commonly performed using aqueous concentrations and aqueous toxicity measurements as a starting point. However risk evaluations could be carried out using internal biotic concentrations and the internal lethal or sublethal concentrations. This has several advantages. Firstly, the internal lethal and sublethal concentrations are relatively consistent in groups of chemicals having a similar mode of action. Thus in field situations the internal concentration, in fish and possibly other biota, can be used to evaluate possible biotic effects. Also other histopathological, biochemical, biomolecular and physiological effects can be assessed and used with this information to give an overall assessment. There are, however, several limitations with this approach including sensitivity, health, age and nutritional status of the biota as well as a lack of data on dose/response relationships with internal concentrations.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherPergamon-Elsevier Science LTD
dc.publisher.placeUK
dc.relation.ispartofpagefrom54
dc.relation.ispartofpageto61
dc.relation.ispartofissue1-12
dc.relation.ispartofjournalMarine Pollution Bulletin
dc.relation.ispartofvolume39
dc.titleImportance of Internal Biotic Concentrations in Risk Evaluations with Aquatic Systems
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.hasfulltextNo Full Text
gro.griffith.authorConnell, Des W.
gro.griffith.authorYu, Jimmy J.
gro.griffith.authorChaisuksant, Yupadee


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