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dc.contributor.authorGlazov, Gregory
dc.contributor.authorYelland, Michael
dc.contributor.authorEmery, Jon
dc.date.accessioned2019-04-15T04:59:15Z
dc.date.available2019-04-15T04:59:15Z
dc.date.issued2016
dc.identifier.issn0964-5284en_US
dc.identifier.urihttp://hdl.handle.net/10072/123717
dc.description.abstractObjective: The efficacy of low-level laser treatment (LLLT) for chronic back pain remains controversial due to insufficient trial data. We aimed to conduct an updated review to determine if LLLT (including laser acupuncture) has specific benefits in chronic non-specific low back pain (CNLBP). Methods: Electronic databases were searched for randomised trials using sham controls and blinded assessment examining the intervention of LLLT in adults with CNLBP. Primary outcomes were pain and global assessment of improvement with up to short-term follow-up. Secondary outcomes were disability, range of back movement, and adverse effects. A random effects meta-analysis was conducted. Subgroup analyses were based on laser dose, duration of baseline pain, and whether or not laser therapy used an acupuncture approach. Results: 15 studies were selected involving 1039 participants. At immediate and short-term follow-up there was significant pain reduction of up to WMD (weighted mean difference) −1.40 cm (95% CI −1.91 to −0.88 cm) in favour of laser treatment, occurring in trials using at least 3 Joules (J) per point, with baseline pain <30 months and in non-acupuncture LLLT trials. Global assessment showed a risk ratio of 2.16 (95% CI 1.61 to 2.90) in favour of laser treatment in the same groups only at immediate follow-up. Conclusions: We demonstrated moderate quality of evidence (GRADE) to support a clinically important benefit in LLLT for CNLBP in the short term, which was only seen following higher laser dose interventions and in participants with a shorter duration of back pain. Rigorously blinded trials using appropriate laser dosage would provide greater certainty around this conclusion.en_US
dc.description.peerreviewedYesen_US
dc.languageEnglishen_US
dc.publisherB M J Groupen_US
dc.publisher.urihttps://journals.sagepub.com/doi/abs/10.1136/acupmed-2015-011036en_US
dc.relation.ispartofpagefrom328en_US
dc.relation.ispartofpageto341en_US
dc.relation.ispartofissue5en_US
dc.relation.ispartofjournalAcupuncture in Medicineen_US
dc.relation.ispartofvolume34en_US
dc.subject.fieldofresearchComplementary and Alternative Medicine not elsewhere classifieden_US
dc.subject.fieldofresearchcode110499en_US
dc.titleLow-level laser therapy for chronic non-specific low back pain: A meta-analysis of randomised controlled trialsen_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Peer Reviewed (HERDC)en_US
dc.type.codeC - Journal Articlesen_US
dcterms.licensehttp://creativecommons.org/licenses/by-nc/4.0/en_US
dc.description.versionPublisheden_US
gro.rights.copyright(c) 2016 Acupunture in Medicine This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/en_US
gro.hasfulltextFull Text
gro.griffith.authorYelland, Michael


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