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dc.contributor.authorZhang, Jun
dc.contributor.authorYan, Sheng
dc.contributor.authorYuan, Dan
dc.contributor.authorAlici, Gursel
dc.contributor.authorNguyen, Nam-trung
dc.contributor.authorLi, Weihua
dc.date.accessioned2018-05-03T01:00:27Z
dc.date.available2018-05-03T01:00:27Z
dc.date.issued2016
dc.identifier.isbn978-0-7918-4965-1
dc.identifier.doi10.1115/MNHMT2016-6717
dc.identifier.urihttp://hdl.handle.net/10072/123730
dc.description.abstractPlasma is a host of various analytes such as proteins, metabolites, circulating nucleic acids (CNAs), pathogens. The key process of plasma extraction is to eliminate the contamination from blood cells. Conventional methods, such as centrifugation and membrane filtration, are generally lab-intensive, time consuming and even dangerous. In this study, we report an integrated microfluidic device that combines inertial microfluidics and membrane filter. The integrated microfluidic device was evaluated by the diluted (x1/10, x1/20) whole blood, and the quality of the extracted blood plasma was tested. It was found that quality of extracted blood plasma from integrated device was equivalent to that obtained by the centrifugation. This study demonstrates a significant progress towards the practical application of inertial microfluidics with membrane filter for high-throughput and high efficient blood plasma extraction.
dc.description.peerreviewedYes
dc.languageEnglish
dc.publisherAmerican Society of Mechanical Engineers (ASME)
dc.publisher.placeUnited States
dc.relation.ispartofconferencename5th ASME International Conference on Micro/Nanoscale Heat and Mass Transfer
dc.relation.ispartofconferencetitlePROCEEDINGS OF THE ASME 5TH INTERNATIONAL CONFERENCE ON MICRO/NANOSCALE HEAT AND MASS TRANSFER, 2016, VOL 1
dc.relation.ispartofdatefrom2016-01-04
dc.relation.ispartofdateto2016-01-06
dc.relation.ispartoflocationBiopolis, SINGAPORE
dc.relation.ispartofvolume1
dc.subject.fieldofresearchMicrotechnology
dc.subject.fieldofresearchcode091009
dc.titleHigh throughput cell-free extraction of plasma by an integrated microfluidic device combining inertial microfluidics and membrane
dc.typeConference output
dc.type.descriptionE1 - Conferences
dc.type.codeE - Conference Publications
gro.rights.copyrightSelf-archiving of the author-manuscript version is not yet supported by this journal. Please refer to the journal link for access to the definitive, published version or contact the author[s] for more information.
gro.hasfulltextNo Full Text
gro.griffith.authorNguyen, Nam-Trung
gro.griffith.authorZhang, Jun


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