Turning metabolomics into drug discovery
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Author(s)
Boufridi, Asmaa
Quinn, Ronald J
Griffith University Author(s)
Year published
2016
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Show full item recordAbstract
Metabolomics is the “omics” that studies the whole metabolome. It has a wide range of
applications, inter alia chemotaxonomy, environmental influences, agriculture, etc. Here we review
the application of metabolomics in natural product research. The importance of physicochemical
properties to drug delivery are discussed in relation to turning metabolomic studies towards drug
discovery. We believe that coupling metabolomic studies with standards of known physicochemical
properties in order to calibrate the chromatographic columns can be beneficial in identifying
compounds of candidate drug quality.Metabolomics is the “omics” that studies the whole metabolome. It has a wide range of
applications, inter alia chemotaxonomy, environmental influences, agriculture, etc. Here we review
the application of metabolomics in natural product research. The importance of physicochemical
properties to drug delivery are discussed in relation to turning metabolomic studies towards drug
discovery. We believe that coupling metabolomic studies with standards of known physicochemical
properties in order to calibrate the chromatographic columns can be beneficial in identifying
compounds of candidate drug quality.
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Journal Title
Journal of the Brazilian Chemical Society
Volume
27
Issue
8
Publisher URI
Copyright Statement
© 2016 Sociedade Brasileira de Química. This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Subject
Chemical sciences
Other chemical sciences not elsewhere classified