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dc.contributor.authorTverdokhlebov, SI
dc.contributor.authorBolbasov, EN
dc.contributor.authorShesterikov, EV
dc.contributor.authorAntonova, LV
dc.contributor.authorGolovkin, AS
dc.contributor.authorMatveeva, VG
dc.contributor.authorPetlin, DG
dc.contributor.authorAnissimov, YG
dc.date.accessioned2018-09-25T23:59:35Z
dc.date.available2018-09-25T23:59:35Z
dc.date.issued2015
dc.identifier.issn0169-4332
dc.identifier.doi10.1016/j.apsusc.2014.12.127
dc.identifier.urihttp://hdl.handle.net/10072/124930
dc.description.abstractSurface modification of polylactic acid (PLLA) by plasma of radio-frequency magnetron discharge with hydroxyapatite target sputtering was investigated. Increased biocompatibility was demonstrated using studies with bone marrow multipotent mesenchymal stromal cells. Atomic force microscopy demonstrates that the plasma treatment modifies the surface morphology of PLLA to produce rougher surface. Infrared spectroscopy and X-ray diffraction revealed that changes in the surface morphology are caused by the processes of PLLA crystallization. Fluorescent X-ray spectroscopy showed that the plasma treatment also changes the chemical composition of PLLA, enriching it with ions of the sputtered target: calcium, phosphorus and oxygen. It is hypothesized that these surface modifications increase biocompatibility of PLLA without increasing toxicity.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherElsevier
dc.relation.ispartofpagefrom32
dc.relation.ispartofpageto39
dc.relation.ispartofjournalApplied Surface Science
dc.relation.ispartofvolume329
dc.subject.fieldofresearchPlasma Physics; Fusion Plasmas; Electrical Discharges
dc.subject.fieldofresearchPolymers and Plastics
dc.subject.fieldofresearchcode020204
dc.subject.fieldofresearchcode091209
dc.titleModification of polylactic acid surface using RF plasma discharge with sputter deposition of a hydroxyapatite target for increased biocompatibility
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
dcterms.licensehttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.description.versionAccepted Manuscript (AM)
gro.rights.copyright© 2015 Elsevier. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International Licence (http://creativecommons.org/licenses/by-nc-nd/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, providing that the work is properly cited.
gro.hasfulltextFull Text
gro.griffith.authorAnissimov, Yuri G.
gro.griffith.authorPetlin, Dan


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