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dc.contributor.authorYeung, W. M.
dc.contributor.authorMcPhail, S. M.
dc.contributor.authorKuys, Suzanne
dc.date.accessioned2018-11-09T01:41:52Z
dc.date.available2018-11-09T01:41:52Z
dc.date.issued2015
dc.identifier.issn1932-2267en_US
dc.identifier.doi10.1007/s11764-015-0435-1en_US
dc.identifier.urihttp://hdl.handle.net/10072/125100
dc.description.abstractIntroduction: Axillary web syndrome (AWS) can result in early post-operative and long-term difficulties following lymphadenectomy for cancer and should be recognised by clinicians. This systematic review was conducted to synthesise information on AWS clinical presentation and diagnosis, frequency, natural progression, grading, pathoaetiology, risk factors, symptoms, interventions and outcomes. Methods: Electronic searches were conducted using Cochrane, Pubmed, MEDLINE, CINAHL, EMBASE, AMED, PEDro and Google Scholar until June 2013. The methodological quality of included studies was determined using the Downs and Black checklist. Narrative synthesis of results was undertaken. Results: Thirty-seven studies with methodological quality scores ranging from 11 to 26 on a 28-point scale were included. AWS diagnosis relies on inspection and palpation; grading has not been validated. AWS frequency was reported in up to 85.4 % of patients. Biopsies identified venous and lymphatic pathoaetiology with five studies suggesting lymphatic involvement. Twenty-one studies reported AWS occurrence within eight post-operative weeks, but late occurrence of greater than 3 months is possible. Pain was commonly reported with shoulder abduction more restricted than flexion. AWS symptoms usually resolve within 3 months but may persist. Risk factors may include extensiveness of surgery, younger age, lower body mass index, ethnicity and healing complications. Low-quality studies suggest that conservative approaches including analgesics, non-steroidal anti-inflammatory drugs and/or physiotherapy may be safe and effective for early symptom reduction. Conclusions: AWS appears common. Current evidence for the treatment of AWS is insufficient to provide clear guidance for clinical practice.en_US
dc.description.peerreviewedYesen_US
dc.languageEnglishen_US
dc.publisherSpringeren_US
dc.relation.ispartofpagefrom576en_US
dc.relation.ispartofpageto598en_US
dc.relation.ispartofissue4en_US
dc.relation.ispartofjournalJournal of Cancer Survivorshipen_US
dc.relation.ispartofvolume9en_US
dc.subject.fieldofresearchOncology and Carcinogenesis not elsewhere classifieden_US
dc.subject.fieldofresearchcode111299en_US
dc.titleA systematic review of axillary web syndrome (AWS)en_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Peer Reviewed (HERDC)en_US
dc.type.codeC - Journal Articlesen_US
gro.hasfulltextNo Full Text
gro.griffith.authorKuys, Suzanne S.


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