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dc.contributor.authorFrancis, G
dc.contributor.authorStein, S
dc.date.accessioned2017-08-28T02:43:02Z
dc.date.available2017-08-28T02:43:02Z
dc.date.issued2015
dc.identifier.issn1661-6596
dc.identifier.doi10.3390/ijms160614122
dc.identifier.urihttp://hdl.handle.net/10072/125159
dc.description.abstractWith the development of new sensitive molecular techniques, circulating cell-free tumour DNA containing mutations can be identified in the plasma of cancer patients. The applications of this technology may result in significant changes to the care and management of cancer patients. Whilst, currently, these “liquid biopsies” are used to supplement the histological diagnosis of cancer and metastatic disease, in the future these assays may replace the need for invasive procedures. Applications include the monitoring of tumour burden, the monitoring of minimal residual disease, monitoring of tumour heterogeneity, monitoring of molecular resistance and early diagnosis of tumours and metastatic disease.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherMDPI
dc.relation.ispartofpagefrom14122
dc.relation.ispartofpageto14142
dc.relation.ispartofissue6
dc.relation.ispartofjournalInternational Journal of Molecular Sciences
dc.relation.ispartofvolume16
dc.subject.fieldofresearchGenetics not elsewhere classified
dc.subject.fieldofresearchOther Chemical Sciences
dc.subject.fieldofresearchGenetics
dc.subject.fieldofresearchOther Biological Sciences
dc.subject.fieldofresearchcode060499
dc.subject.fieldofresearchcode0399
dc.subject.fieldofresearchcode0604
dc.subject.fieldofresearchcode0699
dc.titleCirculating cell-free tumour DNA in the management of cancer
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
dcterms.licensehttp://creativecommons.org/licenses/by/4.0/
dc.description.versionVersion of Record (VoR)
gro.facultyGriffith Health, School of Medicine
gro.rights.copyright© 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
gro.hasfulltextFull Text
gro.griffith.authorFrancis, Glenn D.


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