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dc.contributor.authorAtkinson, Caroline J
dc.contributor.authorZhang, Kai
dc.contributor.authorMunn, Alan L
dc.contributor.authorWiegmans, Adrian
dc.contributor.authorWei, Ming Q
dc.date.accessioned2017-12-13T05:09:54Z
dc.date.available2017-12-13T05:09:54Z
dc.date.issued2016
dc.identifier.issn1933-6896
dc.identifier.doi10.1080/19336896.2015.1110293
dc.identifier.urihttp://hdl.handle.net/10072/125431
dc.description.abstractPrions are infectious proteins and over the past few decades, some prions have become renowned for their causative role in several neurodegenerative diseases in animals and humans. Since their discovery, the mechanisms and mode of transmission and molecular structure of prions have begun to be established. There is, however, still much to be elucidated about prion diseases, including the development of potential therapeutic strategies for treatment. The significance of prion disease is discussed here, including the categories of human and animal prion diseases, disease transmission, disease progression and the development of symptoms and potential future strategies for treatment. Furthermore, the structure and function of the normal cellular prion protein (PrPC) and its importance in not only in prion disease development, but also in diseases such as cancer and Alzheimer's disease will also be discussed.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherTaylor & Francis
dc.relation.ispartofpagefrom1
dc.relation.ispartofpageto8
dc.relation.ispartofjournalPrion
dc.subject.fieldofresearchGene and Molecular Therapy
dc.subject.fieldofresearchBiochemistry and Cell Biology
dc.subject.fieldofresearchcode100401
dc.subject.fieldofresearchcode0601
dc.titlePrion Protein Scrapie and the Normal Cellular Prion Protein
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.facultyGriffith Health, School of Medical Science
gro.description.notepublicThis publication has been entered into Griffith Research Online as an Advanced Online Version.
gro.hasfulltextNo Full Text
gro.griffith.authorAtkinson, Caroline
gro.griffith.authorMunn, Alan L.
gro.griffith.authorWei, Ming Q.
gro.griffith.authorZhang, Kai


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