Show simple item record

dc.contributor.authorHassan, Mohamed Ali Abol
dc.contributor.authorRouf, Razina
dc.contributor.authorTiralongo, Evelin
dc.contributor.authorMay, Tom W
dc.contributor.authorTiralongo, Joe
dc.date.accessioned2017-09-04T04:29:24Z
dc.date.available2017-09-04T04:29:24Z
dc.date.issued2015
dc.identifier.issn1422-0067
dc.identifier.doi10.3390/ijms16047802
dc.identifier.urihttp://hdl.handle.net/10072/132283
dc.description.abstractLectins are non-immunoglobulin proteins that bind diverse sugar structures with a high degree of selectivity. Lectins play crucial role in various biological processes such as cellular signaling, scavenging of glycoproteins from the circulatory system, cell–cell interactions in the immune system, differentiation and protein targeting to cellular compartments, as well as in host defence mechanisms, inflammation, and cancer. Among all the sources of lectins, plants have been most extensively studied. However, more recently fungal lectins have attracted considerable attention due to their antitumor, antiproliferative and immunomodulatory activities. Given that only 10% of mushroom species are known and have been taxonomically classified, mushrooms represent an enormous unexplored source of potentially useful and novel lectins. In this review we provide an up-to-date summary on the biochemical, molecular and structural properties of mushroom lectins, as well as their versatile applications specifically focusing on mushroom lectin bioactivity.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherMDPI
dc.publisher.placeSwitzerland
dc.relation.ispartofpagefrom7802
dc.relation.ispartofpageto7838
dc.relation.ispartofjournalInternational Journal of Molecular Sciences
dc.relation.ispartofvolume16
dc.subject.fieldofresearchStructural Biology (incl. Macromolecular Modelling)
dc.subject.fieldofresearchCellular Interactions (incl. Adhesion, Matrix, Cell Wall)
dc.subject.fieldofresearchOther Chemical Sciences
dc.subject.fieldofresearchGenetics
dc.subject.fieldofresearchOther Biological Sciences
dc.subject.fieldofresearchcode060112
dc.subject.fieldofresearchcode060106
dc.subject.fieldofresearchcode0399
dc.subject.fieldofresearchcode0604
dc.subject.fieldofresearchcode0699
dc.titleMushroom Lectins: Specificity, Structure and Bioactivity Relevant to Human Disease
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
dcterms.licensehttps://creativecommons.org/licenses/by/4.0/
dc.description.versionPublished
gro.facultyOffice of the Snr Dep Vice Chancellor, Institute for Glycomics
gro.rights.copyright© 2015 by the authors; licensee MDPI, author. This is an Open Access article distributed under the terms of the Creative Commons Attribution 3.0 Unported (CC BY 3.0) License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
gro.hasfulltextFull Text
gro.griffith.authorTiralongo, Joe
gro.griffith.authorTiralongo, Evelin
gro.griffith.authorRouf, Razina
gro.griffith.authorAbol Hassan, Ali


Files in this item

This item appears in the following Collection(s)

  • Journal articles
    Contains articles published by Griffith authors in scholarly journals.

Show simple item record