Morphological and molecular analysis of a breast cancer cluster at the ABC Studio in Toowong

View/ Open
File version
Accepted Manuscript (AM)
Author(s)
Waddell, N
Stein, SR
Wagner, SA
Bennett, I
Djougarian, A
Melana, S
Jaffer, S
Holland, JF
Pogo, BGT
Gonda, TJ
Brown, MA
Leo, P
Saunders, NA
McMillan, NA
Cocciardi, S
Vargas, AC
Lakhani, SR
Chenevix-Trench, G
Newman, B
Francis, GD
Griffith University Author(s)
Year published
2012
Metadata
Show full item recordAbstract
Cancer clusters involving small numbers of patients are relatively common, but only a few have been investigated. In the case of breast cancer, for some putative clusters no significant increase in the risk of developing cancer has been found,1 and in only a minority of cancer clusters which are found to be statistically significant is a causative agent found. Two such studies have shown an increased risk in breast cancer in office workers exposed to strong magnetic fields.2,3 How-ever, for many cancer clusters, although a common aetiology was not proven, it could not be discounted, highlighting the difficulty in definitively ...
View more >Cancer clusters involving small numbers of patients are relatively common, but only a few have been investigated. In the case of breast cancer, for some putative clusters no significant increase in the risk of developing cancer has been found,1 and in only a minority of cancer clusters which are found to be statistically significant is a causative agent found. Two such studies have shown an increased risk in breast cancer in office workers exposed to strong magnetic fields.2,3 How-ever, for many cancer clusters, although a common aetiology was not proven, it could not be discounted, highlighting the difficulty in definitively associating a causal agent to a cancer cluster.4,5
View less >
View more >Cancer clusters involving small numbers of patients are relatively common, but only a few have been investigated. In the case of breast cancer, for some putative clusters no significant increase in the risk of developing cancer has been found,1 and in only a minority of cancer clusters which are found to be statistically significant is a causative agent found. Two such studies have shown an increased risk in breast cancer in office workers exposed to strong magnetic fields.2,3 How-ever, for many cancer clusters, although a common aetiology was not proven, it could not be discounted, highlighting the difficulty in definitively associating a causal agent to a cancer cluster.4,5
View less >
Journal Title
Pathology
Volume
44
Issue
5
Copyright Statement
© 2012 Elsevier. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International Licence, which permits unrestricted, non-commercial use, distribution and reproduction in any medium, providing that the work is properly cited.
Subject
Clinical sciences