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dc.contributor.authorH. Warnke, Patrick
dc.contributor.authorT. Becker, Stephan
dc.contributor.authorN. G. Springer, Ingo
dc.contributor.authorHarle, Franz
dc.contributor.authorUllmann, Uwe
dc.contributor.authorA. J. Russo, Paul
dc.contributor.authorWiltfang, Jorg
dc.contributor.authorFickenscher, Helmut
dc.contributor.authorSchubert, Sabine
dc.date.accessioned2019-03-11T01:10:03Z
dc.date.available2019-03-11T01:10:03Z
dc.date.issued2008
dc.identifier.issn03057453
dc.identifier.doi10.1093/jac/dkn030
dc.identifier.urihttp://hdl.handle.net/10072/140803
dc.description.abstractAlthough dental health in the developed world is improving, patients with acute dentoalveolar or odontogenic abscesses still present frequently at dental surgeries or emergency units.1 Following its discovery by Fleming in 1928,2 penicillin has long been recognized as an effective standard therapy in patients with orofacial infections. However, penicillin is no longer in favour3 due to the more frequent isolation of resistant bacteria from abscesses of odontogenic origin.4,5 Therefore, alternative antibiotics such as erythromycin, clindamycin, tetracycline and levofloxacin have been considered and recommended for patients with failure of penicillin regimen or allergy.4,6 Newer studies recommend levofloxacin or moxifloxacin, modern 8-methoxyquinolone antibiotics, as potential rational choices for odontogenic infections, due to high in vitro activity against oral pathogens.7 Therefore, we are ascending the ladder of our antibiotic weaponry, unfortunately simultaneously increasing the risk of further resistance to these additional classes of drugs. But do these in vitro investigations correlate with common day-to-day clinical experience?
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherOxford University Press
dc.publisher.placeUnited Kingdom
dc.relation.ispartofpagefrom960
dc.relation.ispartofpageto962
dc.relation.ispartofissue4
dc.relation.ispartofjournalJournal of Antimicrobial Chemotherapy
dc.relation.ispartofvolume61
dc.subject.fieldofresearchDentistry not elsewhere classified
dc.subject.fieldofresearchMicrobiology
dc.subject.fieldofresearchMedical Microbiology
dc.subject.fieldofresearchPharmacology and Pharmaceutical Sciences
dc.subject.fieldofresearchcode110599
dc.subject.fieldofresearchcode0605
dc.subject.fieldofresearchcode1108
dc.subject.fieldofresearchcode1115
dc.title'Grandmother penicillin' - Not in vogue, but clinically still effective
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.hasfulltextNo Full Text
gro.griffith.authorWarnke, Patrick H.


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