dc.contributor.author | Alayan, Jamil | |
dc.contributor.author | Vaquette, Cedryck | |
dc.contributor.author | Saifzadeh, Siamak | |
dc.contributor.author | Hutmacher, Dietmar | |
dc.contributor.author | Ivanovski, Saso | |
dc.date.accessioned | 2018-07-18T03:11:07Z | |
dc.date.available | 2018-07-18T03:11:07Z | |
dc.date.issued | 2016 | |
dc.identifier.issn | 0905-7161 | |
dc.identifier.doi | 10.1111/clr.12652 | |
dc.identifier.uri | http://hdl.handle.net/10072/141216 | |
dc.description.abstract | Objective: To histomorphometrically compare the use of collagen-stabilized anorganic bovine
bone (ABBM-C) (test) to anorganic bovine bone + autogenous bone (ABBM + AB) (control) in
maxillary sinus augmentation.
Materials and methods: Nine sheep underwent bilateral sinus augmentation. Each sinus was
randomized to receive either control or test bone graft. Three animals were sacrificed at 8 weeks,
and six animals were sacrificed at 16 weeks post-grafting. The 18 sinuses were processed for
histomorphometry, which assessed the area fraction of new bone (%NB), residual graft (%RG) and
soft tissue components (% STM), as well as graft particle osseointegration (% OI), within three
zones equally distributed from the augmented sinus floor.
Results: At week 16, a significant increase in %NB was evident across all three zones in the control
group when compared to week 8. A significantly greater %NB was evident in the control group
when compared to the test group in zones 2 (P < 0.001) and 3 (P < 0.001). There was a significant
increase in %OI in week 16 when compared to week 8 across all three zones in the control group
(P < 0.001). %OI in the control group was significantly greater across all three zones when
compared to the test group at week 16 (P < 0.001). Zone was found to be a significant main effect
(P < 0.001) that was independent of time and treatment with decreasing %OI in distant zones. %
RG did not significantly change with time for both groups. There was a significant reduction in %
ST in week 16 when compared to week 8 across all three zones in the control group (P < 0.001). %
ST in the test group was significantly greater across all zones when compared to the control group
at week 16 (P < 0.001).
Conclusion: Both groups exhibited very similar histomorphometric measurements in the zones
proximal to the resident sinus wall. The % NB and % OI were greatest in the zones proximal to
resident bony walls and gradually decreased as the distance from the proximal walls increased.
There was greater % NB and % OI in the control group when compared to the test group in the
distant zone. | |
dc.description.peerreviewed | Yes | |
dc.language | English | |
dc.language.iso | eng | |
dc.publisher | Wiley-Blackwell Publishing | |
dc.relation.ispartofpagefrom | 734 | |
dc.relation.ispartofpageto | 743 | |
dc.relation.ispartofissue | 6 | |
dc.relation.ispartofjournal | Clinical Oral Implants Research | |
dc.relation.ispartofvolume | 27 | |
dc.subject.fieldofresearch | Biomedical engineering | |
dc.subject.fieldofresearch | Dentistry | |
dc.subject.fieldofresearch | Dentistry not elsewhere classified | |
dc.subject.fieldofresearchcode | 4003 | |
dc.subject.fieldofresearchcode | 3203 | |
dc.subject.fieldofresearchcode | 320399 | |
dc.title | A histomorphometric assessment of collagen-stabilized anorganic bovine bone mineral in maxillary sinus augmentation - a randomized controlled trial in sheep | |
dc.type | Journal article | |
dc.type.description | C1 - Articles | |
dc.type.code | C - Journal Articles | |
gro.faculty | Griffith Health, School of Dentistry and Oral Health | |
gro.hasfulltext | No Full Text | |
gro.griffith.author | Ivanovski, Saso | |
gro.griffith.author | Alayan, Jamil | |
gro.griffith.author | Vaquette, Cedryck | |
gro.griffith.author | Hutmacher, Dietmar W. | |