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dc.contributor.authorLajhar, SA
dc.contributor.authorJennison, AV
dc.contributor.authorPatel, B
dc.contributor.authorDuffy, LL
dc.date.accessioned2018-01-03T22:51:13Z
dc.date.available2018-01-03T22:51:13Z
dc.date.issued2015
dc.identifier.issn0950-2688
dc.identifier.doi10.1017/S0950268815000886
dc.identifier.urihttp://hdl.handle.net/10072/141248
dc.description.abstractCampylobacter jejuni is responsible for most foodborne bacterial infections worldwide including Australia. The aim of this study was to investigate a combination of typing methods in the characterization of C. jejuni isolated from clinical diarrhoeal samples (n = 20) and chicken meat (n = 26) in order to identify the source of infection and rank isolates based on their relative risk to humans. Sequencing of the flaA short variable region demonstrated that 86% of clinical isolates had genotypes that were also found in chicken meat. A polymerase chain reaction binary typing system identified 27 different codes based on the presence or absence of genes that have been reported to be associated with various aspects of C. jejuni pathogenicity, indicating that not all isolates may be of equal risk to human health. The lipooligosaccharide (LOS) of the C. jejuni isolates was classified into six classes (A, B, C, E, F, H) with 10·4% remaining unclassified. The majority (72·7%) of clinical isolates possessed sialylated LOS classes. Sialylated LOS classes were also detected in chicken isolates (80·7%). Antimicrobial tests indicated a low level of resistance, with no phenotypic resistance found to most antibiotics tested. A combination of typing approaches was useful to assign isolates to a source of infection and assess their risk to humans.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherCambridge University Press
dc.relation.ispartofpagefrom3498
dc.relation.ispartofpageto3509
dc.relation.ispartofissue16
dc.relation.ispartofjournalEpidemiology and Infection
dc.relation.ispartofvolume143
dc.subject.fieldofresearchPublic Health and Health Services not elsewhere classified
dc.subject.fieldofresearchPublic Health and Health Services
dc.subject.fieldofresearchcode111799
dc.subject.fieldofresearchcode1117
dc.titleComparison of epidemiologically linked Campylobacter jejuni isolated from human and poultry sources
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.facultyGriffith Sciences, School of Natural Sciences
gro.hasfulltextNo Full Text
gro.griffith.authorPatel, Bharat K.
gro.griffith.authorLajhar, Salma A. Ibsais AI.


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