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dc.contributor.authorBeck, Belinda R
dc.date.accessioned2017-06-13T04:35:10Z
dc.date.available2017-06-13T04:35:10Z
dc.date.issued2015
dc.identifier.issn1544-1873
dc.identifier.doi10.1007/s11914-015-0294-8
dc.identifier.urihttp://hdl.handle.net/10072/141337
dc.description.abstractA considerable volume of evidence has accumulated to suggest that whole-body vibration (WBV) may have a therapeutic role to play in the prevention of osteoporotic fracture, particularly for individuals who are unable to tolerate vigorous exercise interventions. There is moderate to strong evidence that WBV will prevent falls (likely due to enhanced neuromuscular function), but also some indication that the effects of WBV do not outstrip those of targeted exercise. Animal data indicates that WBV will also improve bone mass, including preventing loss due to hormone withdrawal, disuse and glucocorticoid exposure. Human trials, however, have produced equivocal outcomes for bone. Positive trends are apparent at the hip and spine, but shortcomings in study designs have limited statistical power. The mechanism of the vibration effect on bone tissue is likely to be mechanical coupling between an oscillating cell nucleus and the cytoskeleton. More robust dose-response human data are required before therapeutic guidelines can be developed.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherSpringer Healthcare
dc.relation.ispartofpagefrom381
dc.relation.ispartofpageto389
dc.relation.ispartofissue6
dc.relation.ispartofjournalCurrent Osteoporosis Reports
dc.relation.ispartofvolume13
dc.subject.fieldofresearchClinical sciences
dc.subject.fieldofresearchRehabilitation
dc.subject.fieldofresearchcode3202
dc.subject.fieldofresearchcode420109
dc.titleVibration Therapy to Prevent Bone Loss and Falls: Mechanisms and Efficacy
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
dc.description.versionAccepted Manuscript (AM)
gro.rights.copyright© 2015 Springer Science+Business Media New York. This is an electronic version of an article published in Current Osteoporosis Reports, Volume 13, Issue 6, pp 381–389, 2015. Current Osteoporosis Reports is available online at: http://link.springer.com/ with the open URL of your article.
gro.hasfulltextFull Text
gro.griffith.authorBeck, Belinda R.


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