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dc.contributor.authorKurtboeke, D Ipek
dc.contributor.authorFrench, John RJ
dc.contributor.authorHayes, R Andrew
dc.contributor.authorQuinn, Ronald J
dc.contributor.editorMukherjee, J
dc.date.accessioned2017-12-12T01:52:25Z
dc.date.available2017-12-12T01:52:25Z
dc.date.issued2015
dc.identifier.isbn978-3-662-45096-3
dc.identifier.doi10.1007/10_2014_270
dc.identifier.urihttp://hdl.handle.net/10072/141706
dc.description.abstractTermites play a major role in foraging and degradation of plant biomass as well as cultivating bioactive microorganisms for their defense. Current advances in “omics” sciences are revealing insights into function-related presence of these symbionts, and their related biosynthetic activities and genes identified in gut symbiotic bacteria might offer a significant potential for biotechnology and biodiscovery. Actinomycetes have been the major producers of bioactive compounds with an extraordinary range of biological activities. These metabolites have been in use as anticancer agents, immune suppressants, and most notably, as antibiotics. Insect-associated actinomycetes have also been reported to produce a range of antibiotics such as dentigerumycin and mycangimycin. Advances in genomics targeting a single species of the unculturable microbial members are currently aiding an improved understanding of the symbiotic interrelationships among the gut microorganisms as well as revealing the taxonomical identity and functions of the complex multilayered symbiotic actinofloral layers. If combined with target-directed approaches, these molecular advances can provide guidance towards the design of highly selective culturing methods to generate further information related to the physiology and growth requirements of these bioactive actinomycetes associated with the termite guts. This chapter provides an overview on the termite gut symbiotic actinoflora in the light of current advances in the “omics” science, with examples of their detection and selective isolation from the guts of the Sunshine Coast regional termite Coptotermes lacteus in Queensland, Australia.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherSpringer Berlin Heidelberg
dc.publisher.placeGermany
dc.relation.ispartofbooktitleBiotechnological Applications of Biodiversity
dc.relation.ispartofchapter4
dc.relation.ispartofpagefrom111
dc.relation.ispartofpageto136
dc.subject.fieldofresearchMedicinal and biomolecular chemistry not elsewhere classified
dc.subject.fieldofresearchcode340499
dc.titleEco-Taxonomic Insights into Actinomycete Symbionts of Termites for Discovery of Novel Bioactive Compounds
dc.typeBook chapter
dc.type.descriptionB1 - Chapters
dc.type.codeB - Book Chapters
gro.hasfulltextNo Full Text
gro.griffith.authorQuinn, Ronald J.


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