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dc.contributor.authorDavoren, P
dc.date.accessioned2017-08-28T23:07:52Z
dc.date.available2017-08-28T23:07:52Z
dc.date.issued2015
dc.identifier.issn0300-8495
dc.identifier.urihttp://hdl.handle.net/10072/141815
dc.description.abstractBackground: There is an increasing array of medicines available to improve blood glucose control in type 2 diabetes. Finding the best com-bination for an individual patient requires an assessment of the patient’s characteristics and understanding the mechanism of action for each drug. Objective/s: The aim of this article is to provide a rational approach for choosing between the various blood glucose-lowering medicines available for treatment of patients with type 2 diabetes mellitus. Discussion: Metformin is the first choice of glucose-lowering medicines for most patients with type 2 diabetes. Sulphonylureas have proven benefits in long-term trials. Insulin is required in patients with symptoms of insulin deficiency. Glucagon-like peptide 1 agonists and sodium-glucose co-transporter 2 inhibitors provide some assistance in weight loss as well as improving blood glucose con-trol. Dipeptidyl peptidase 4 inhibitors provide an alternative to metformin and sulphonylureas, especially when side effects of those drugs limit their use. Re-assessing blood glucose control after an appropriate trial period before deciding on continuing use is appropriate.
dc.description.peerreviewedYes
dc.languageeng
dc.publisherRoyal Australian College of General Practitioners
dc.publisher.placeAustralia
dc.publisher.urihttp://www.racgp.org.au/afp/2015/may/glucose-lowering-medicines-for-type-2-diabetes/
dc.relation.ispartofpagefrom272
dc.relation.ispartofpageto276
dc.relation.ispartofissue5
dc.relation.ispartofjournalAustralian Family Physician
dc.relation.ispartofvolume44
dc.subject.fieldofresearchMedical and Health Sciences not elsewhere classified
dc.subject.fieldofresearchClinical Sciences
dc.subject.fieldofresearchPublic Health and Health Services
dc.subject.fieldofresearchcode119999
dc.subject.fieldofresearchcode1103
dc.subject.fieldofresearchcode1117
dc.titleGlucose-lowering medicines for type 2 diabetes
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
dc.description.versionPublished
gro.facultyGriffith Health, School of Medicine
gro.rights.copyright© 2015 Australian Family Physician. Reproduced with permission. Permission to reproduce must be sought from the publisher, The Royal Australian College of General Practitioners.
gro.hasfulltextFull Text
gro.griffith.authorDavoren, Peter M.


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