TCM, brain function and drug space
Author(s)
Tang, Chunping
Ye, Yang
Feng, Yunjiang
Quinn, Ronald J
Year published
2016
Metadata
Show full item recordAbstract
Traditional Chinese medicine has played a significant role in the mainstream healthcare system in China for thousands of years. Here, we summarize 84 major compounds from 15 selected herbal medicines targeting neurodegenerative diseases. We present a perspective based on the analysis of physicochemical properties of these TCM compounds, and comparison with current drugs and candidates for the treatment of Parkinson's and Alzheimer's disease. The results demonstrate that traditional Chinese medicines contain compounds possessing physicochemical properties that have excellent overlap with developed western medicines.Traditional Chinese medicine has played a significant role in the mainstream healthcare system in China for thousands of years. Here, we summarize 84 major compounds from 15 selected herbal medicines targeting neurodegenerative diseases. We present a perspective based on the analysis of physicochemical properties of these TCM compounds, and comparison with current drugs and candidates for the treatment of Parkinson's and Alzheimer's disease. The results demonstrate that traditional Chinese medicines contain compounds possessing physicochemical properties that have excellent overlap with developed western medicines.
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Journal Title
Natural Product Reports
Volume
33
Issue
1
Subject
Chemical sciences
Medicinal and biomolecular chemistry not elsewhere classified
Biological sciences
Biomedical and clinical sciences