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dc.contributor.authorKhan, Suliman
dc.contributor.authorNabi, Ghulam
dc.contributor.authorNaeem, Muhammad
dc.contributor.authorAli, Liaqat
dc.contributor.authorSilburn, Peter A
dc.contributor.authorMellick, George D
dc.date.accessioned2018-01-05T04:28:49Z
dc.date.available2018-01-05T04:28:49Z
dc.date.issued2016
dc.identifier.issn1178-2021
dc.identifier.doi10.2147/NDT.S86329
dc.identifier.urihttp://hdl.handle.net/10072/142477
dc.description.abstractIntroduction: Parkinson’s disease (PD) occurs in all races and cultures, and population-related differences in frequency may provide etiological clues. The present study was designed to explore the prevalence of PD and Parkinsonism in Pakistan, the world’s sixth most populous country, for which no published prevalence data are available. Methods: We conducted a three-phase door-to-door survey in two districts of the Khyber Pakhtunkhwa province of Pakistan, to assess the prevalence of PD and Parkinsonism in a sample of 4,000 individuals aged 50 years and above. Results: We identified 14 cases of Parkinsonism, eleven with a diagnosis of idiopathic PD. The overall prevalence estimates were 1.7/100 (95% confidence interval [CI]: 0.9-2.46) for Parkinsonism and 1.28/100 (95% CI: 0.6-1.94) for PD in persons aged 65 years and above. The age-standardized prevalence of PD (aged 65 years and above), normalized to the USA population in 2000, was 1.33/100, which is similar to that observed in other human populations. Of the total 14 cases, five were newly diagnosed and four had a family history of PD. Conclusion: The estimated prevalence rates in Pakistan are similar to those observed in other human populations. The frequency of familial Parkinsonism is also equivalent to previous estimates.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherDove Medical Press Ltd.
dc.relation.ispartofpagefrom1499
dc.relation.ispartofpageto1506
dc.relation.ispartofjournalNeuropsychiatric Disease and Treatment
dc.relation.ispartofvolume12
dc.subject.fieldofresearchNeurosciences not elsewhere classified
dc.subject.fieldofresearchClinical Sciences
dc.subject.fieldofresearchNeurosciences
dc.subject.fieldofresearchcode110999
dc.subject.fieldofresearchcode1103
dc.subject.fieldofresearchcode1109
dc.titleA door-to-door survey to estimate the prevalence of Parkinsonism in Pakistan
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
dcterms.licensehttp://creativecommons.org/licenses/by-nc/3.0/
dc.description.versionVersion of Record (VoR)
gro.facultyGriffith Sciences, Griffith Institute for Drug Discovery
gro.rights.copyright© 2016 Khan et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License. The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. Permissions beyond the scope of the License are administered by Dove Medical Press Limited. Information on how to request permission may be found at: http://www.dovepress.com/permissions.php
gro.hasfulltextFull Text
gro.griffith.authorSilburn, Peter A.
gro.griffith.authorMellick, George
gro.griffith.authorKhan, Suliman


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