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dc.contributor.authorKhosravi-Boroujeni, Hossein
dc.contributor.authorAhmed, Faruk
dc.contributor.authorSarrafzadegan, Nizal
dc.date.accessioned2018-04-25T23:00:09Z
dc.date.available2018-04-25T23:00:09Z
dc.date.issued2015
dc.identifier.issn0300-9831
dc.identifier.doi10.1024/0300-9831/a000277
dc.identifier.urihttp://hdl.handle.net/10072/143256
dc.description.abstractThe incidence of metabolic syndrome (MetS) has been increasing globally and it is recognized as a major public health problem because MetS is associated with increased risk of diabetes, stroke, cancer, and other chronic diseases. Recently, MetS has been linked to vitamin D deficiency. However, the evidence on the association between vitamin D deficiency and the risk of MetS remains inconclusive. This review therefore aims to depict the existing evidence related to MetS and vitamin D deficiency, and examined some of the possible confounders which may affect the association between vitamin D status and risk of MetS. Earlier studies on the association between vitamin D deficiency and MetS have adjusted for the effect of some confounders including, age, sex, body mass index, race, physical activity, smoking, alcohol consumption, and energy intake. However, these studies failed to consider other potential confounders. There is evidence that vitamin A, zinc (Zn), and magnesium (Mg) play important roles in the activation and function of vitamin D and interact with gene expression. Furthermore, these micronutrients are also related to several components of the MetS including glucose intolerance, dyslipidemia, and obesity. Thus, there could be an interaction between these micronutrients, vitamin D, and MetS. This review highlights the possible interactions of vitamin A, Zn, Mg, and vitamin D with MetS and its components. The findings reinforce the need for further well-designed studies that take into account all potential confounders, including other micronutrients such as vitamin A, Zn, and Mg status, to investigate the independent association of vitamin D status with MetS and its components, and also to scrutinize for possible interactions among other nutrients which may have similar confounding effects.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherVerlag Hans Huber AG
dc.relation.ispartofpagefrom1
dc.relation.ispartofpageto16
dc.relation.ispartofjournalInternational Journal for Vitamin and Nutrition Research
dc.subject.fieldofresearchNutrition and dietetics
dc.subject.fieldofresearchNutrition and dietetics not elsewhere classified
dc.subject.fieldofresearchcode3210
dc.subject.fieldofresearchcode321099
dc.titleIs the Association between Vitamin D and Metabolic Syndrome Independent of Other Micronutrients
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
dc.description.versionAccepted Manuscript (AM)
gro.facultyGriffith Health, School of Medicine
gro.description.notepublicThis publication has been entered into Griffith Research Online as an Advanced Online Version.
gro.rights.copyright© 2016 Hogrefe & Huber Publishers. This is the author-manuscript version of this paper. Reproduced in accordance with the copyright policy of the publisher. This article may not exactly replicate the final version published in European Journal of Psychological Assessment. It is not the version of record and is therefore not suitable for citation.
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gro.griffith.authorAhmed, Faruk


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