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  • Naseseazine C, a new anti-plasmodial dimeric diketopiperazine from a marine sediment derived Streptomyces sp.

    Author(s)
    Buedenbender, Larissa
    Grkovic, Tanja
    Duffy, Sandra
    Kurtboke, D Ipek
    Avery, Vicky M
    Carroll, Anthony R
    Griffith University Author(s)
    Carroll, Anthony R.
    Duffy, Sandra
    Avery, Vicky M.
    Year published
    2016
    Metadata
    Show full item record
    Abstract
    A new dimeric diketopiperazine, naseseazine C, and the known naseseazines A and B were isolated from solid culture extracts of an Australian marine sediment derived Streptomyces species. Naseseazine C displayed a new C-6′/C-3 linkage between the two diketopiperazine subunits and showed moderate activity against the chloroquine-sensitive malaria parasite, Plasmodium falciparum (3D7 strain).A new dimeric diketopiperazine, naseseazine C, and the known naseseazines A and B were isolated from solid culture extracts of an Australian marine sediment derived Streptomyces species. Naseseazine C displayed a new C-6′/C-3 linkage between the two diketopiperazine subunits and showed moderate activity against the chloroquine-sensitive malaria parasite, Plasmodium falciparum (3D7 strain).
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    Journal Title
    Tetrahedron Letters
    Volume
    57
    Issue
    52
    DOI
    https://doi.org/10.1016/j.tetlet.2016.11.071
    Subject
    Medicinal and biomolecular chemistry
    Medicinal and biomolecular chemistry not elsewhere classified
    Organic chemistry
    Biochemistry and cell biology
    Publication URI
    http://hdl.handle.net/10072/143678
    Collection
    • Journal articles

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