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dc.contributor.authorIvanovski, S
dc.contributor.authorGronthos, S
dc.contributor.authorShi, S
dc.contributor.authorBartold, PM
dc.contributor.editorBruce Baum, Crispian Scully
dc.date.accessioned2019-03-14T04:55:36Z
dc.date.available2019-03-14T04:55:36Z
dc.date.issued2006
dc.identifier.issn1354-523X
dc.identifier.doi10.1111/j.1601-0825.2006.01253.x
dc.identifier.urihttp://hdl.handle.net/10072/147612
dc.description.abstractThe ability to identify and manipulate stem cells has been a significant advancement in regenerative medicine and has contributed to the development of tissue engineering‐based clinical therapies. Difficulties associated with achieving predictable periodontal regeneration, means that novel techniques such as tissue engineering need to be developed in order to regenerate the extensive soft and hard tissue destruction that results from periodontitis. One of the critical requirements for a tissue engineering approach is the delivery of ex vivo expanded progenitor populations or the mobilization of endogenous progenitor cells capable of proliferating and differentiating into the required tissues. By definition, stem cells fulfill these requirements and the recent identification of stem cells within the periodontal ligament represents a significant development in the progress toward predictable periodontal regeneration. In order to explore the importance of stem cells in periodontal wound healing and regeneration, this review will examine contemporary concepts in stem cell biology, the role of periodontal ligament progenitor cells in the regenerative process, recent developments in identifying periodontal stem cells and the clinical implications of these findings.
dc.languageEnglish
dc.language.isoeng
dc.publisherBlackwell Munksgaard
dc.publisher.placeDenmark
dc.relation.ispartofpagefrom358
dc.relation.ispartofpageto363
dc.relation.ispartofvolume12
dc.subject.fieldofresearchDentistry
dc.subject.fieldofresearchcode3203
dc.titleStem cells in the peridontal ligament
dc.typeReport
dc.type.descriptionU2 - Reviews/Reports
dc.type.codeC - Journal Articles
dc.description.versionAccepted Manuscript (AM)
gro.facultyGriffith Health, School of Dentistry and Oral Health
gro.rights.copyright© 2006 John Wiley & Sons A/S. This is the peer reviewed version of the following article: Stem cells in the periodontal ligament, Oral Diseases, Volume 12, Issue 4, July 2006, Pages 358-363, which has been published in final form at https://doi.org/10.1111/j.1601-0825.2006.01253.x. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving (http://olabout.wiley.com/WileyCDA/Section/id-828039.html)
gro.hasfulltextFull Text
gro.griffith.authorIvanovski, Saso


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