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dc.contributor.convenorBiotechnology Industry Organization
dc.contributor.authorMcDonnell, Ann
dc.contributor.editorBiotechnology Industry Organization
dc.date.accessioned2017-05-03T12:57:52Z
dc.date.available2017-05-03T12:57:52Z
dc.date.issued2006
dc.date.modified2009-10-08T06:27:52Z
dc.identifier.urihttp://hdl.handle.net/10072/14883
dc.description.abstractPresently, there is no cure for central nervous system damage. The use of various biocompatible materials is being investigated to guide neural and glial cells to repair damaged nerves. Biocompatible materials must be capable of being used in or on the human body without eliciting a rejection response from the surrounding body tissues. They must pass stringent tests to assure that they will not cause inflammation, infection, thrombogenesis, adverse immunological response or neoplastic induction or promotion. We have developed and optimized a process to apply to a biocompatible fibre that possesses minimal immunogenicity and can withstand modification and sterilization procedures, plus maintain its integrity throughout long-term tissue culture in vitro. In tests to date, the biocompatible fibres have lasted for periods of longer than 6 months in continuous in vitro cell culture conditions. The scaffold appears to be ideal in enhancing the linearization and the directional migration of cells, particularly those of neural and glial origins. Such a property would be superlative in the field of tissue engineering, especially from the perspective of nerve regeneration and repair. The biocompatible fibre (cell seeded or unseeded) has been shown in vitro to enhance glial and neuronal directional alignments, and aid in the growth of lineated nerve tissue, which may be more suitable and conducive for nerve and spinal cord repair The poster will present more information on the outcomes of the current studies conducted. Griffith is seeking a commercial and research relationship with companies in the field of tissue engineering and in particular those with specific interest in nerve regeneration and repair. Contact Dr Ann McDonnell at A.McDonnell@griffith.edu.au or Brian Smith on +61 (0) 754 742.
dc.description.publicationstatusYes
dc.languageEnglish
dc.language.isoeng
dc.publisherBiotechnology Industry Organization
dc.publisher.placeChicago, USA
dc.publisher.urihttp://www.bio.org/
dc.publisher.urihttp://www.bio.org/events/
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofconferencenameBIO 2006 Annual International Convention
dc.relation.ispartofconferencetitleInnovation Corridor Abstract: Biocompatible Fibres Promote Lineated Growth and Migration of Neural Progenitor Cells With Potential Applications In Nerve Bioregeneration
dc.relation.ispartofdatefrom2006-04-09
dc.relation.ispartofdateto2006-04-12
dc.relation.ispartoflocationChicago, USA
dc.rights.retentionY
dc.subject.fieldofresearchcode270899
dc.titleBiocompatible Fibres Promote Lineated Growth and Migration of Neural Progenitor Cells With Potential Applications In Nerve Bioregeneration
dc.typeConference output
dc.type.descriptionE3 - Conferences (Extract Paper)
dc.type.codeE - Conference Publications
gro.facultyGriffith Sciences, School of Natural Sciences
gro.date.issued2006
gro.hasfulltextNo Full Text
gro.griffith.authorMcDonnell, Ann A.


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    Contains papers delivered by Griffith authors at national and international conferences.

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