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dc.contributor.authorCantacessi, Cinzia
dc.contributor.authorHofmann, Andreas
dc.contributor.authorCampbell, Bronwyn E
dc.contributor.authorGasser, Robin B
dc.contributor.editorCunha, MV
dc.contributor.editorInacio, J
dc.date.accessioned2018-01-22T00:51:24Z
dc.date.available2018-01-22T00:51:24Z
dc.date.issued2015
dc.identifier.isbn978-1-4939-2003-7
dc.identifier.doi10.1007/978-1-4939-2004-4_31
dc.identifier.urihttp://hdl.handle.net/10072/152430
dc.description.abstractHigh-throughput molecular and computer technologies have become instrumental for systems biological explorations of pathogens, including parasites. For instance, investigations of the transcriptomes of different developmental stages of parasitic nematodes give insights into gene expression, regulation and function in a parasite, which is a significant step to understanding their biology, as well as interactions with their host(s) and disease. This chapter (1) gives a background on some key parasitic nematodes of socioeconomic importance, (2) describes sequencing and bioinformatic technologies for large-scale studies of the transcriptomes and genomes of these parasites, (3) provides some recent examples of applications and (4) emphasizes the prospects of fundamental biological explorations of parasites using these technologies for the development of new interventions to combat parasitic diseases.
dc.description.peerreviewedYes
dc.languageEnglish
dc.publisherSpringer
dc.publisher.placeUnited States
dc.relation.ispartofbooktitleVeterinary Infection Biology: Molecular Diagnostics and High-Throughput Strategies, Methods in Molecular Biology
dc.relation.ispartofchapter31
dc.relation.ispartofpagefrom437
dc.relation.ispartofpageto474
dc.relation.ispartofvolume1247
dc.subject.fieldofresearchMedical Parasitology
dc.subject.fieldofresearchOther Chemical Sciences
dc.subject.fieldofresearchBiochemistry and Cell Biology
dc.subject.fieldofresearchcode110803
dc.subject.fieldofresearchcode0399
dc.subject.fieldofresearchcode0601
dc.titleImpact of next-generation technologies on exploring socio-economically important parasites and developing new interventions
dc.typeBook chapter
dc.type.descriptionB1 - Chapters
dc.type.codeB - Book Chapters
dc.description.versionPost-print
gro.rights.copyright© 2015 Springer. This is the author-manuscript version of this paper. It is reproduced here in accordance with the copyright policy of the publisher. Please refer to the publisher’s website for further information.
gro.hasfulltextFull Text
gro.griffith.authorHofmann, Andreas


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