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dc.contributor.authorBarclay, Chrisen_US
dc.contributor.authorLichtwark, Glenen_US
dc.date.accessioned2017-04-04T15:03:15Z
dc.date.available2017-04-04T15:03:15Z
dc.date.issued2007en_US
dc.identifier.issn00219290en_US
dc.identifier.doi10.1016/j.jbiomech.2007.03.024en_US
dc.identifier.urihttp://hdl.handle.net/10072/16051
dc.description.abstractThe dynamic properties of relaxing skeletal muscle have not been well characterised but are important for understanding muscle function during terrestrial locomotion, during which a considerable fraction of muscle work output can be produced during relaxation. The purpose of this study was to characterise the force-velocity properties of mouse skeletal muscle during relaxation. Experiments were performed in vitro (21 1C) using bundles of fibres from mouse soleus and EDL muscles. Isovelocity shortening was applied to muscles during relaxation following short tetanic contractions. Using data from different contractions with different shortening velocities, curves relating force output to shortening velocity were constructed at intervals during relaxation. The velocity component included contributions from shortening of both series elastic component (SEC) and contractile component (CC) because force output was not constant. Early in relaxation force-velocity relationships were linear but became progressively more curved as relaxation progressed. Force-velocity curves late in relaxation had the same curvature as those for the CC in fully activated muscles but Vmax was reduced to %50 of the value in fully activated muscles. These results were the same for slow- and fast-twitch muscles and for relaxation following maximal tetani and brief, sub-maximal tetani. The measured series elastic compliance was used to partition shortening velocity between SEC and CC. The curvature of the CC force-velocity relationship was constant during relaxation. The SEC accounted for most of the shortening and work output during relaxation and its power output during relaxation exceeded the maximum CC power output. It is proposed that unloading the CC, without any change in its overall length, accelerated cross-bridge detachment when shortening was applied during relaxation.en_US
dc.description.peerreviewedYesen_US
dc.description.publicationstatusYesen_US
dc.languageEnglishen_US
dc.language.isoen_US
dc.publisherElsevieren_US
dc.publisher.placeOxforden_US
dc.relation.ispartofstudentpublicationNen_US
dc.relation.ispartofpagefrom3121en_US
dc.relation.ispartofpageto3129en_US
dc.relation.ispartofjournalJournal of Biomechanicsen_US
dc.relation.ispartofvolume40en_US
dc.rights.retentionYen_US
dc.subject.fieldofresearchcode270602en_US
dc.titleThe mechanics of mouse skeletal muscle when shortening during relaxationen_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Peer Reviewed (HERDC)en_US
dc.type.codeC - Journal Articlesen_US
gro.facultyGriffith Health, School of Rehabilitation Sciencesen_US
gro.date.issued2015-05-11T05:39:10Z
gro.hasfulltextNo Full Text


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