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dc.contributor.authorBarclay, Chris
dc.contributor.authorLichtwark, Glen
dc.date.accessioned2017-05-03T11:39:53Z
dc.date.available2017-05-03T11:39:53Z
dc.date.issued2007
dc.identifier.issn00219290
dc.identifier.doi10.1016/j.jbiomech.2007.03.024
dc.identifier.urihttp://hdl.handle.net/10072/16051
dc.description.abstractThe dynamic properties of relaxing skeletal muscle have not been well characterised but are important for understanding muscle function during terrestrial locomotion, during which a considerable fraction of muscle work output can be produced during relaxation. The purpose of this study was to characterise the force-velocity properties of mouse skeletal muscle during relaxation. Experiments were performed in vitro (21 1C) using bundles of fibres from mouse soleus and EDL muscles. Isovelocity shortening was applied to muscles during relaxation following short tetanic contractions. Using data from different contractions with different shortening velocities, curves relating force output to shortening velocity were constructed at intervals during relaxation. The velocity component included contributions from shortening of both series elastic component (SEC) and contractile component (CC) because force output was not constant. Early in relaxation force-velocity relationships were linear but became progressively more curved as relaxation progressed. Force-velocity curves late in relaxation had the same curvature as those for the CC in fully activated muscles but Vmax was reduced to %50 of the value in fully activated muscles. These results were the same for slow- and fast-twitch muscles and for relaxation following maximal tetani and brief, sub-maximal tetani. The measured series elastic compliance was used to partition shortening velocity between SEC and CC. The curvature of the CC force-velocity relationship was constant during relaxation. The SEC accounted for most of the shortening and work output during relaxation and its power output during relaxation exceeded the maximum CC power output. It is proposed that unloading the CC, without any change in its overall length, accelerated cross-bridge detachment when shortening was applied during relaxation.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.languageEnglish
dc.language.isoeng
dc.publisherElsevier
dc.publisher.placeOxford
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrom3121
dc.relation.ispartofpageto3129
dc.relation.ispartofjournalJournal of Biomechanics
dc.relation.ispartofvolume40
dc.rights.retentionY
dc.subject.fieldofresearchBiomedical Engineering
dc.subject.fieldofresearchMechanical Engineering
dc.subject.fieldofresearchHuman Movement and Sports Sciences
dc.subject.fieldofresearchcode0903
dc.subject.fieldofresearchcode0913
dc.subject.fieldofresearchcode1106
dc.titleThe mechanics of mouse skeletal muscle when shortening during relaxation
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.facultyGriffith Health, School of Rehabilitation Sciences
gro.date.issued2015-05-11T05:39:10Z
gro.hasfulltextNo Full Text
gro.griffith.authorBarclay, Chris
gro.griffith.authorLichtwark, Glen A.


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