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dc.contributor.authorDjohan, Djohan
dc.contributor.authorYu, Jimmy
dc.contributor.authorConnell, Des
dc.contributor.authorChristensen, Elizabeth
dc.date.accessioned2019-02-05T01:47:52Z
dc.date.available2019-02-05T01:47:52Z
dc.date.issued2007
dc.date.modified2009-09-01T05:58:29Z
dc.identifier.issn1528-7394
dc.identifier.doi10.1080/15287390701432384
dc.identifier.urihttp://hdl.handle.net/10072/17059
dc.description.abstractA human health risk assessment was performed to evaluate the risks due to chlorobenzenes in the air of residential houses. Chlorobenzenes found in the air in the toilets, rooms, and outdoors of three houses in Brisbane, Australia, were sampled by trapping on Tenax TA and analyzed using an automated thermal desorption (ATD)-gas chromatography/mass spectrometry (GC/MS) method. Concentrations of 1,4-dichlorobenzene (1,4-DCB) in the rooms, toilets, and outdoors were used as the exposure concentrations (E), while those in the toilets (姯m3) were used as the high-exposure concentrations (HE). The exposure concentrations were transformed into exposure doses (EXDE and EXDHE). Dose-response data from the literature for a range of adverse effects in animals were obtained and exposure doses were expressed as human equivalent dose (HED). The HED values were higher than the EXDE and EXDHE values for all adverse effects, and a hazard quotient was calculated that indicated a low level of risk with the high-exposure environment. The lifetime average daily doses (LADDs) for a wide range of adverse effects observed in human case studies were estimated and compared to the doses in the high-exposure (HE) situation. Using the Monte Carlo simulation technique the probabilities of risk quotients higher than unity ranged from 0.02 to 0.26. This evaluation indicated that 1,4-DCB posed low risks to general residents; however, for individuals with susceptible characteristics and exposure to elevated 1,4-DCB, the probability of adverse responses was moderate to high.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.languageEnglish
dc.language.isoeng
dc.publisherTaylor and Francis
dc.publisher.placeLondon
dc.publisher.urihttps://taylorandfrancis.com/
dc.relation.ispartofstudentpublicationY
dc.relation.ispartofpagefrom1594
dc.relation.ispartofpageto1603
dc.relation.ispartofjournalJournal of Toxicology and Environmental Health. Part A
dc.relation.ispartofvolume70
dc.rights.retentionY
dc.subject.fieldofresearchChemical sciences
dc.subject.fieldofresearchEnvironmental sciences
dc.subject.fieldofresearchBiomedical and clinical sciences
dc.subject.fieldofresearchcode34
dc.subject.fieldofresearchcode41
dc.subject.fieldofresearchcode32
dc.titleHealth risk assessment of chlorobenzenes in the air of residential houses using probabilistic techniques
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.facultyGriffith Sciences, Griffith School of Engineering
gro.date.issued2007
gro.hasfulltextNo Full Text
gro.griffith.authorConnell, Des W.
gro.griffith.authorYu, Jimmy J.


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