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dc.contributor.authorNavarro-Torne, Adoracion
dc.contributor.authorDias, Joana Comes
dc.contributor.authorHruba, Frantiska
dc.contributor.authorLopalco, Pier Luigi
dc.contributor.authorPastore-Celentano, Lucia
dc.contributor.authorGauci, Andrew J Amato
dc.date.accessioned2017-07-27T01:30:43Z
dc.date.available2017-07-27T01:30:43Z
dc.date.issued2015
dc.identifier.issn1080-6040
dc.identifier.doi10.3201/eid2103.140634
dc.identifier.urihttp://hdl.handle.net/10072/172004
dc.description.abstractWe studied the possible association between patient age and sex, clinical presentation, Streptococcus pneumoniae serotype, antimicrobial resistance, and death in invasive pneumococcal disease cases reported by 17 European countries during 2010. The study sample comprised 2,921 patients, of whom 56.8% were men and 38.2% were >65 years of age. Meningitis occurred in 18.5% of cases. Death was reported in 264 (9.0%) cases. Older age, meningitis, and nonsusceptibility to penicillin were significantly associated with death. Non–pneumococcal conjugate vaccine (PCV) serotypes among children <5 years of age and 7-valent PCV serotypes among persons 5–64 years of age were associated with increased risk for death; among adults >65 years of age, risk did not differ by serotype. These findings highlight differences in case-fatality rates between serotypes and age; thus, continued epidemiologic surveillance across all ages is crucial to monitor the long-term effects of PCVs.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherU.S. Department of Health and Human Services
dc.relation.ispartofpagefrom417
dc.relation.ispartofpageto425
dc.relation.ispartofissue3
dc.relation.ispartofjournalEmerging Infectious Diseases
dc.relation.ispartofvolume21
dc.subject.fieldofresearchPublic Health and Health Services not elsewhere classified
dc.subject.fieldofresearchClinical Sciences
dc.subject.fieldofresearchMedical Microbiology
dc.subject.fieldofresearchPublic Health and Health Services
dc.subject.fieldofresearchcode111799
dc.subject.fieldofresearchcode1103
dc.subject.fieldofresearchcode1108
dc.subject.fieldofresearchcode1117
dc.titleRisk factors for death from invasive pneumococcal disease, Europe, 2010
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
dc.description.versionVersion of Record (VoR)
gro.rights.copyright© 2015 Centers for Disease Control and Prevention. The attached file is reproduced here in accordance with the copyright policy of the publisher. Please refer to the journal's website for access to the definitive, published version.
gro.hasfulltextFull Text
gro.griffith.authorSlack, Mary P.


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