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dc.contributor.authorHarrison, Odile B
dc.contributor.authorBrueggemann, Angela B
dc.contributor.authorCaugant, Dominique A
dc.contributor.authorvan der Ende, Arie
dc.contributor.authorFrosch, Matthias
dc.contributor.authorGray, Stephen
dc.contributor.authorHeuberger, Sigrid
dc.contributor.authorKrizova, Paula
dc.contributor.authorOlcen, Per
dc.contributor.authorSlack, Mary
dc.contributor.authorTaha, Muhamed-Kheir
dc.contributor.authorMaiden, Martin CJ
dc.date.accessioned2018-05-08T02:30:43Z
dc.date.available2018-05-08T02:30:43Z
dc.date.issued2011
dc.identifier.issn1350-0872
dc.identifier.doi10.1099/mic.0.050518-0
dc.identifier.urihttp://hdl.handle.net/10072/172048
dc.description.abstractInvasive disease caused by the encapsulated bacteria Neisseria meningitidis, Haemophilus influenzae and Streptococcus pneumoniae remains an important cause of morbidity and mortality worldwide, despite the introduction of successful conjugate polysaccharide vaccines that target disease-associated strains. In addition, resistance, or more accurately reduced susceptibility, to therapeutic antibiotics is spreading in populations of these organisms. There is therefore a continuing requirement for the surveillance of vaccine and non-vaccine antigens and antibiotic susceptibilities among isolates from invasive disease, which is only partially met by conventional methods. This need can be met with molecular and especially nucleotide sequence-based typing methods, which are fully developed in the case of N. meningitidis and which could be more widely deployed in clinical laboratories for S. pneumoniae and H. influenzae.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherSociety for General Microbiology
dc.relation.ispartofpagefrom2181
dc.relation.ispartofpageto2195
dc.relation.ispartofissue8
dc.relation.ispartofjournalMicrobiology
dc.relation.ispartofvolume157
dc.subject.fieldofresearchMedical microbiology not elsewhere classified
dc.subject.fieldofresearchcode320799
dc.titleMolecular typing methods for outbreak detection and surveillance of invasive disease caused by Neisseria meningitidis, Haemophilus influenzae and Streptococcus pneumoniae, a review
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.hasfulltextNo Full Text
gro.griffith.authorSlack, Mary P.


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