Femtomolar Detection of a Cancer Biomarker Protein in Serum with Ultralow Background Current by Anodic Stripping Voltammetry
Author(s)
Shiddiky, Muhammad JA
Kithva, Prakash H
Rauf, Sakandar
Trau, Matt
Griffith University Author(s)
Year published
2012
Metadata
Show full item recordAbstract
An electrochemical immunosensor for the detection of a cancer biomarker protein in serum at femtomolar concentrations with ultralow background response has been developed, which consists of (i) a hydrophilic polyacrylic acid brush-modified indium tin oxide substrate as an antifouling substrate and (ii) a graphene–quantum dots–antibody ‘bionanoconjugate’ as a signal amplification label in voltammetric detection of targets in a glassy carbon electrode.An electrochemical immunosensor for the detection of a cancer biomarker protein in serum at femtomolar concentrations with ultralow background response has been developed, which consists of (i) a hydrophilic polyacrylic acid brush-modified indium tin oxide substrate as an antifouling substrate and (ii) a graphene–quantum dots–antibody ‘bionanoconjugate’ as a signal amplification label in voltammetric detection of targets in a glassy carbon electrode.
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Journal Title
Chemical Communications
Volume
48
Issue
51
Subject
Chemical sciences
Analytical chemistry not elsewhere classified