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  • Femtomolar Detection of a Cancer Biomarker Protein in Serum with Ultralow Background Current by Anodic Stripping Voltammetry

    Author(s)
    Shiddiky, Muhammad JA
    Kithva, Prakash H
    Rauf, Sakandar
    Trau, Matt
    Griffith University Author(s)
    Shiddiky, Muhammad J.
    Year published
    2012
    Metadata
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    Abstract
    An electrochemical immunosensor for the detection of a cancer biomarker protein in serum at femtomolar concentrations with ultralow background response has been developed, which consists of (i) a hydrophilic polyacrylic acid brush-modified indium tin oxide substrate as an antifouling substrate and (ii) a graphene–quantum dots–antibody ‘bionanoconjugate’ as a signal amplification label in voltammetric detection of targets in a glassy carbon electrode.An electrochemical immunosensor for the detection of a cancer biomarker protein in serum at femtomolar concentrations with ultralow background response has been developed, which consists of (i) a hydrophilic polyacrylic acid brush-modified indium tin oxide substrate as an antifouling substrate and (ii) a graphene–quantum dots–antibody ‘bionanoconjugate’ as a signal amplification label in voltammetric detection of targets in a glassy carbon electrode.
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    Journal Title
    Chemical Communications
    Volume
    48
    Issue
    51
    DOI
    https://doi.org/10.1039/c2cc32810k
    Subject
    Chemical sciences
    Analytical chemistry not elsewhere classified
    Publication URI
    http://hdl.handle.net/10072/172455
    Collection
    • Journal articles

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