Core-Shell Upconversion Nanoparticle@Metal-Organic Framework Nanoprobes for Luminescent/Magnetic Dual-Mode Targeted Imaging

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Author(s)
Li, Yantao
Tang, Jinglong
He, Liangcan
Liu, Yong
Liu, Yaling
Chen, Chunying
Tang, Zhiyong
Griffith University Author(s)
Year published
2015
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Core–shell upconversion nanoparticle@metal–organic framework (UCNP@MOF) nanostructures are constructed by coating hexagonal NaYF4:Yb,Er nanoparticle (NP) cores with amino-functionalized iron carboxylate MOF shells. These nanostructures combine the near-infrared optical property of the UCNP cores and the T2-magnetic response (MR) imaging property of the MOF shells. After surface modification, the core–shell nanostructures are demonstrated as high-resolution nanoprobes for targeted luminescence/MR imaging both in vitro and in vivo.Core–shell upconversion nanoparticle@metal–organic framework (UCNP@MOF) nanostructures are constructed by coating hexagonal NaYF4:Yb,Er nanoparticle (NP) cores with amino-functionalized iron carboxylate MOF shells. These nanostructures combine the near-infrared optical property of the UCNP cores and the T2-magnetic response (MR) imaging property of the MOF shells. After surface modification, the core–shell nanostructures are demonstrated as high-resolution nanoprobes for targeted luminescence/MR imaging both in vitro and in vivo.
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Journal Title
Advanced Materials
Volume
27
Issue
27
Copyright Statement
© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. This is the peer reviewed version of the following article: Core-Shell Upconversion Nanoparticle@Metal-Organic Framework Nanoprobes for Luminescent/Magnetic Dual-Mode Targeted Imaging, Advanced Materials, Volume 27, Issue 27,Pages 4075–4080, 2015, which has been published in final form at 10.1002/adma.201501779. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving (http://olabout.wiley.com/WileyCDA/Section/id-828039.html)
Subject
Physical sciences
Chemical sciences
Engineering
Materials engineering not elsewhere classified