dc.contributor.author | Mawad, Damia | |
dc.contributor.author | Warren, Charles | |
dc.contributor.author | Barton, M. | |
dc.contributor.author | Mahns, David | |
dc.contributor.author | Morley, John | |
dc.contributor.author | Pham, Binh T.T. | |
dc.contributor.author | Pham, Nguyen T.H. | |
dc.contributor.author | Kueh, Sindy | |
dc.contributor.author | Lauto, Antonio | |
dc.date.accessioned | 2018-12-03T23:41:41Z | |
dc.date.available | 2018-12-03T23:41:41Z | |
dc.date.issued | 2015 | |
dc.identifier.issn | 0144-8617 | |
dc.identifier.doi | 10.1016/j.carbpol.2014.12.008 | |
dc.identifier.uri | http://hdl.handle.net/10072/173135 | |
dc.description.abstract | Effective tissue bioadhesion of rose bengal–chitosan films can be achieved by photoactivation using a green laser. In this study, lysozyme was incorporated in these films to enhance the rate of depolymerization and assess the laser impact on lysozyme. The lysozyme loaded films exhibited a 21% mass loss after 4 weeks implantation in rats while control films (without lysozyme) had only 7% mass loss. Capillary electrophoresis–mass spectroscopy showed that chitosan degraded into monomers and oligomers of glucosamine and N-acetyl-glucosamine. Irradiation with laser did not affect the depolymerization of adhesive by lysozyme suggesting that the inclusion of lysozyme in the bioadhesive is a viable technique for tailoring the depolymerization. | |
dc.description.peerreviewed | Yes | |
dc.language | English | |
dc.language.iso | eng | |
dc.publisher | Pergamon Press | |
dc.relation.ispartofpagefrom | 56 | |
dc.relation.ispartofpageto | 63 | |
dc.relation.ispartofjournal | Carbohydrate Polymers | |
dc.relation.ispartofvolume | 121 | |
dc.subject.fieldofresearch | Macromolecular and materials chemistry | |
dc.subject.fieldofresearch | Organic chemistry | |
dc.subject.fieldofresearch | Food sciences | |
dc.subject.fieldofresearch | Surgery | |
dc.subject.fieldofresearchcode | 3403 | |
dc.subject.fieldofresearchcode | 3405 | |
dc.subject.fieldofresearchcode | 3006 | |
dc.subject.fieldofresearchcode | 320226 | |
dc.title | Lysozyme depolymerization of photo-activated chitosan adhesive films | |
dc.type | Journal article | |
dc.type.description | C1 - Articles | |
dc.type.code | C - Journal Articles | |
gro.hasfulltext | No Full Text | |
gro.griffith.author | Barton, Matthew J. | |