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dc.contributor.authorMawad, Damia
dc.contributor.authorWarren, Charles
dc.contributor.authorBarton, M.
dc.contributor.authorMahns, David
dc.contributor.authorMorley, John
dc.contributor.authorPham, Binh T.T.
dc.contributor.authorPham, Nguyen T.H.
dc.contributor.authorKueh, Sindy
dc.contributor.authorLauto, Antonio
dc.date.accessioned2018-12-03T23:41:41Z
dc.date.available2018-12-03T23:41:41Z
dc.date.issued2015
dc.identifier.issn0144-8617
dc.identifier.doi10.1016/j.carbpol.2014.12.008
dc.identifier.urihttp://hdl.handle.net/10072/173135
dc.description.abstractEffective tissue bioadhesion of rose bengal–chitosan films can be achieved by photoactivation using a green laser. In this study, lysozyme was incorporated in these films to enhance the rate of depolymerization and assess the laser impact on lysozyme. The lysozyme loaded films exhibited a 21% mass loss after 4 weeks implantation in rats while control films (without lysozyme) had only 7% mass loss. Capillary electrophoresis–mass spectroscopy showed that chitosan degraded into monomers and oligomers of glucosamine and N-acetyl-glucosamine. Irradiation with laser did not affect the depolymerization of adhesive by lysozyme suggesting that the inclusion of lysozyme in the bioadhesive is a viable technique for tailoring the depolymerization.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherPergamon Press
dc.relation.ispartofpagefrom56
dc.relation.ispartofpageto63
dc.relation.ispartofjournalCarbohydrate Polymers
dc.relation.ispartofvolume121
dc.subject.fieldofresearchMacromolecular and materials chemistry
dc.subject.fieldofresearchOrganic chemistry
dc.subject.fieldofresearchFood sciences
dc.subject.fieldofresearchSurgery
dc.subject.fieldofresearchcode3403
dc.subject.fieldofresearchcode3405
dc.subject.fieldofresearchcode3006
dc.subject.fieldofresearchcode320226
dc.titleLysozyme depolymerization of photo-activated chitosan adhesive films
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.hasfulltextNo Full Text
gro.griffith.authorBarton, Matthew J.


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