dc.contributor.author | Heneghan, C | |
dc.contributor.author | Blacklock, C | |
dc.contributor.author | Perera, R | |
dc.contributor.author | Davis, R | |
dc.contributor.author | Banerjee, A | |
dc.contributor.author | Gill, P | |
dc.contributor.author | Liew, S | |
dc.contributor.author | Chamas, L | |
dc.contributor.author | Hernandez, J | |
dc.contributor.author | Mahtani, K | |
dc.contributor.author | Hayward, G | |
dc.contributor.author | Harrison, S | |
dc.contributor.author | Lasserson, D | |
dc.contributor.author | Mickan, S | |
dc.contributor.author | Sellers, C | |
dc.contributor.author | Carnes, D | |
dc.contributor.author | Homer, K | |
dc.contributor.author | Steed, L | |
dc.contributor.author | Ross, J | |
dc.contributor.author | Denny, N | |
dc.contributor.author | Goyder, C | |
dc.contributor.author | Thompson, M | |
dc.contributor.author | Ward, A | |
dc.date.accessioned | 2018-01-19T01:15:20Z | |
dc.date.available | 2018-01-19T01:15:20Z | |
dc.date.issued | 2013 | |
dc.identifier.issn | 2044-6055 | |
dc.identifier.doi | 10.1136/bmjopen-2013-003298 | |
dc.identifier.uri | http://hdl.handle.net/10072/173513 | |
dc.description.abstract | Introduction: Prevalence of non-communicable
diseases (NCDs) is increasing globally, with the
greatest projected increases in low-income and middleincome
countries. We sought to quantify the
proportion of Cochrane evidence relating to NCDs
derived from such countries.
Methods: We searched the Cochrane database of
systematic reviews for reviews relating to NCDs
highlighted in the WHO NCD action plan
(cardiovascular, cancers, diabetes and chronic
respiratory diseases). We excluded reviews at the
protocol stage and those that were repeated or had
been withdrawn. For each review, two independent
researchers extracted data relating to the country of
the corresponding author and the number of trials
and participants from countries, using the
World Bank classification of gross national income per
capita.
Results: 797 reviews were analysed, with a reported
total number of 12 340 trials and 10 937 306
participants. Of the corresponding authors 90%
were from high-income countries (41% from the UK).
Of the 746 reviews in which at least one trial had
met the inclusion criteria, only 55% provided a
summary of the country of included trials. Analysis
of the 633 reviews in which country of trials could
be established revealed that almost 90% of trials
and over 80% of participants were from high-income
countries. 438 (5%) trials including 1 145 013 (11.7%)
participants were undertaken in low-middle income
countries. We found that only 13 (0.15%) trials with
982 (0.01%) participants were undertaken in lowincome
countries. Other than the five Cochrane
NCD corresponding authors from South Africa, only
one other corresponding author was from Africa
(Gambia).
Discussion: The overwhelming body of evidence for
NCDs pertains to high-income countries, with only a
small number of review authors based in low-income
settings. As a consequence, there is an urgent need for
research infrastructure and funding for the undertaking
of high-quality trials in this area. | |
dc.description.peerreviewed | Yes | |
dc.language | English | |
dc.language.iso | eng | |
dc.publisher | BMJ Publishing Group | |
dc.relation.ispartofpagefrom | e003298-1 | |
dc.relation.ispartofpageto | e003298-8 | |
dc.relation.ispartofissue | 7 | |
dc.relation.ispartofjournal | BMJ Open | |
dc.relation.ispartofvolume | 3 | |
dc.subject.fieldofresearch | Clinical sciences | |
dc.subject.fieldofresearch | Clinical sciences not elsewhere classified | |
dc.subject.fieldofresearch | Other health sciences | |
dc.subject.fieldofresearchcode | 3202 | |
dc.subject.fieldofresearchcode | 320299 | |
dc.subject.fieldofresearchcode | 4299 | |
dc.title | Evidence for non-communicable diseases: Analysis of Cochrane reviews and randomised trials by World Bank classification | |
dc.type | Journal article | |
dc.type.description | C1 - Articles | |
dc.type.code | C - Journal Articles | |
dcterms.license | http://creativecommons.org/licenses/by-nc/3.0/ | |
dc.description.version | Version of Record (VoR) | |
gro.rights.copyright | © 2013 This final article is available
for use under the terms of
the Creative Commons
Attribution Non-Commercial
3.0 Licence; see
http://bmjopen.bmj.com | |
gro.hasfulltext | Full Text | |
gro.griffith.author | Mickan, Sharon M. | |