Aporphine Alkaloids from the Chinese Tree Neolitsea aurata var. paraciculata

Abstract

Three new oxygenated noraporphine alkaloids were isolated from the bark of the Chinese tree Neolitsea aurata var. paraciculata. The new compounds, (+)-11-methoxynorcassythicine, (+)-11-methoxynorneolitsine, (+)-11-methoxynorboldine, were isolated along with eight known aporphine alkaloids, hernovine, ovigerine, N-methylovigerine, 10-O-methylhernovine, lindcarpine, N,O-dimethylhernovine, laurolitsine and nandigerine. Their structures were determined by 1D and 2D NMR spectroscopy. This is the first report of chemical constituents from N. aurata var. paraciculata.