Show simple item record

dc.contributor.authorOwen, Daviden_US
dc.contributor.authorDavis, Chrisen_US
dc.contributor.authorHartnell, Reganen_US
dc.contributor.authorMadge, Paulen_US
dc.contributor.authorThomson, Robinen_US
dc.contributor.authorChong, Andrewen_US
dc.contributor.authorL. Coppel, Rossen_US
dc.contributor.authorvon Itzstein, Marken_US
dc.contributor.editorD.L. Boger, L. Ghosez and M. Shibasakien_US
dc.date.accessioned2017-04-24T07:56:32Z
dc.date.available2017-04-24T07:56:32Z
dc.date.issued2007en_US
dc.date.modified2009-09-21T05:50:20Z
dc.identifier.issn0960894Xen_US
dc.identifier.doi10.1016/j.bmcl.2007.01.068en_AU
dc.identifier.urihttp://hdl.handle.net/10072/18268
dc.description.abstractThe recent emergence of clinically oppressive superbugs, some with resistance to nearly all frontline drug therapies, has challenged our ability to combat such infectious organisms as Mycobacterium tuberculosis, the causative agent of tuberculosis (TB). Our medicinal chemistry program targeting this pathogen has identified several potent galactofuranose-based in vitro inhibitors of mycobacterial growth. The most potent compound, the Galf N,N-didecyl sulfenamide 8d, displayed anti-mycobacterial activity (MIC) of 1 姯mL in a cell based assay against a representative strain of Mycobacterium smegmatis.en_US
dc.description.peerreviewedYesen_US
dc.description.publicationstatusYesen_AU
dc.languageEnglishen_US
dc.language.isoen_AU
dc.publisherPergamon Pressen_US
dc.publisher.placeOxford, UKen_US
dc.publisher.urihttp://www.elsevier.com/wps/find/journaldescription.cws_home/972/description#descriptionen_AU
dc.relation.ispartofstudentpublicationNen_AU
dc.relation.ispartofpagefrom2274en_US
dc.relation.ispartofpageto2277en_US
dc.relation.ispartofissue8en_US
dc.relation.ispartofjournalBioorganic & Medicinal Chemistry Lettersen_US
dc.relation.ispartofvolume17en_US
dc.rights.retentionYen_AU
dc.subject.fieldofresearchcode250301en_US
dc.titleSynthesis and evaluation of galactofuranosyl N,N-dialkyl sulfenamides and sulfonamides as antimycobacterial agentsen_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Peer Reviewed (HERDC)en_US
dc.type.codeC - Journal Articlesen_US
gro.date.issued2007
gro.hasfulltextNo Full Text


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

  • Journal articles
    Contains articles published by Griffith authors in scholarly journals.

Show simple item record