Show simple item record

dc.contributor.authorLoh, EW
dc.contributor.authorTang, NLS
dc.contributor.authorLee, DTS
dc.contributor.authorLiu, SI
dc.contributor.authorStadlin, Alfreda
dc.date.accessioned2017-05-03T15:04:51Z
dc.date.available2017-05-03T15:04:51Z
dc.date.issued2007
dc.identifier.issn1552-4841
dc.identifier.doi10.1002/ajmg.b.30429
dc.identifier.urihttp://hdl.handle.net/10072/18802
dc.description.abstractGABAA receptor subunit genes clustered on 5q33 play a role in the development of alcoholism and methamphetamine use disorder without psychosis. The present study explored the possible contribution of the same subunit genes to the development of heroin dependence. Single nucleotide polymorphisms (SNPs) of the GABAA receptor subunits GABRB2, GABRA6, GABRA1, and GABRG2 were examined in 178 male Han Chinese heroin-dependent and 170 male control subjects. A significant difference in allele frequency for the SNP rs211014 in the GABAA 2 receptor subunit gene between cases and controls was identified (P = 0.015). A possible mechanism for the involvement of the GABA receptor subunit genes on 5q33 in the development of heroin dependence is discussed.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.languageEnglish
dc.language.isoeng
dc.publisherWiley-Liss
dc.publisher.placeHoboken, N.J.
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrom439
dc.relation.ispartofpageto443
dc.relation.ispartofissue4
dc.relation.ispartofjournalAmerican Journal of Medical Genetics. Part B: Neuropsychiatric Genetics
dc.relation.ispartofvolume144B
dc.rights.retentionY
dc.subject.fieldofresearchGenetics
dc.subject.fieldofresearchClinical sciences
dc.subject.fieldofresearchNeurosciences
dc.subject.fieldofresearchcode3105
dc.subject.fieldofresearchcode3202
dc.subject.fieldofresearchcode3209
dc.titleAssociation analysis of GABA receptor subunit genes on 5q33 with heroin dependence in a Chinese male population
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.date.issued2015-02-04T04:26:50Z
gro.hasfulltextNo Full Text
gro.griffith.authorStadlin, Alfreda


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

  • Journal articles
    Contains articles published by Griffith authors in scholarly journals.

Show simple item record