Probing Molecular Shape. 1. Conformational Studies of 5-hydroxyhexahydropyrimidine and Related Compounds
MetadataShow full item record
Understanding the factors that determine molecular shape enables scientists to begin to understand and tailor molecular properties and reactivity. Many biomolecules and bioactive compounds contain aliphatic heterocyclic rings whose conformations play a major role in their biological activity. The interplay of a number of factors, both steric and electronic, is examined for 5-hydroxyhexahydropyrimidine (1) and related compounds with use of spectroscopy and molecular modeling.
Journal of Organic Chemistry
© 2007 American Chemical Society. Self-archiving of the author-manuscript version is not yet supported by this publisher. The contents of this journal can be freely accessed online via the ACS web page. Use hypertext link above to access the ACS website.